PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3700413-6 1986 Time-dependent inhibition of aromatization by 10 beta-difluoromethylestr-4-ene-3,17-dione and 10 beta-(2-propynyl)estr-4-ene,3,17-dione was abolished by substitution of a methylene function for the C-3 oxygen, suggesting that the presence of an oxygen at C-3 is required for an oxidative transformation at C-19, an initial step in aromatization. beta-(2-propynyl)estr-4-ene 97-124 complement C3 Homo sapiens 198-201 3700413-6 1986 Time-dependent inhibition of aromatization by 10 beta-difluoromethylestr-4-ene-3,17-dione and 10 beta-(2-propynyl)estr-4-ene,3,17-dione was abolished by substitution of a methylene function for the C-3 oxygen, suggesting that the presence of an oxygen at C-3 is required for an oxidative transformation at C-19, an initial step in aromatization. beta-(2-propynyl)estr-4-ene 97-124 complement C3 Homo sapiens 255-258