PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10630826-11	1999	We propose that the drop in blood pressure with dobutamine in this patient was caused by a fall in systemic vascular resistance due to vascular beta2-adrenergic receptor activation.	Dobutamine	48-58	adrenoceptor beta 2	Homo sapiens	144-169	
11325192-2	2001	Several purported agonists, including isoproterenol, epinephrine, norepinephine, dobutamine, salbutamol, and terbutaline, exhibited dual-affinity displacement curves, which is characteristic of agonist binding to betaAR.	Dobutamine	81-91	adrenoceptor beta 2	Homo sapiens	213-219	
15023079-3	2004	In the present study, PWR has been used to monitor the incorporation of the human beta(2)-adrenergic receptor into a solid-supported egg phosphatidylcholine lipid bilayer and to follow the binding of full agonists (isoproterenol, epinephrine), a partial agonist (dobutamine), an antagonist (alprenolol), and an inverse agonist (ICI-118,551) to the receptor.	Dobutamine	263-273	adrenoceptor beta 2	Homo sapiens	82-109	
12462555-12	2002	Because glucose production is enhanced by alpha1- and beta2-adrenoceptor stimulation, we conclude that dobutamine is only a weak agonist at these adrenoceptors.	Dobutamine	103-113	adrenoceptor beta 2	Homo sapiens	42-72	
3310640-8	1987	Furthermore, in the vasculature, the beta 2-adrenoceptor-mediated vasodilatory effect of dobutamine is exactly offset by the alpha 1-adrenoceptor-mediated vasoconstrictor activity, such that net changes in blood pressure are minimal following the administration of dobutamine.	Dobutamine	89-99	adrenoceptor beta 2	Homo sapiens	37-56	
9843736-6	1998	The lipolytic effects of epinephrine, isoprenaline (beta-adrenoceptor agonist), and dobutamine (beta1-adrenoceptor agonist) were significantly increased (P < 0.05) but not those of procaterol (beta2-adrenoceptor agonist).	Dobutamine	84-94	adrenoceptor beta 2	Homo sapiens	196-214	
9295336-5	1997	The coupling efficiencies for betaAR agonist activation of adenylyl cyclase relative to epinephrine (100%) were 42% for fenoterol, 4.9% for albuterol, 2.5% for dobutamine, and 1.1% for ephedrine.	Dobutamine	160-170	adrenoceptor beta 2	Homo sapiens	30-36	
9295336-6	1997	At concentrations of these agonists yielding >90% receptor occupancy, the rate and extent (0-30 min) of agonist-induced desensitization of betaAR activation of adenylyl cyclase followed the same order as coupling efficiency, i.e. epinephrine >/= fenoterol > albuterol > dobutamine > ephedrine.	Dobutamine	282-292	adrenoceptor beta 2	Homo sapiens	142-148	
35437830-2	2022	METHODS: Alleles in the known genetic single nucleotide polymorphisms in beta1 and beta2 adrenoceptor (AR) genes and Gs protein alpha-subunit gene (GNAS) possibly affecting inotropic effect were identified in patients of neonatal dobutamine pharmacokinetic-pharmacodynamic study.	Dobutamine	230-240	adrenoceptor beta 2	Homo sapiens	83-101	
3310640-8	1987	Furthermore, in the vasculature, the beta 2-adrenoceptor-mediated vasodilatory effect of dobutamine is exactly offset by the alpha 1-adrenoceptor-mediated vasoconstrictor activity, such that net changes in blood pressure are minimal following the administration of dobutamine.	Dobutamine	265-275	adrenoceptor beta 2	Homo sapiens	37-56	
18253135-5	2008	beta(2)-AR Glu27 homozygotes had a greater HR response at the highest dobutamine dose than Gln27 carriers (P=0.002).	Dobutamine	70-80	adrenoceptor beta 2	Homo sapiens	0-10	
21561432-8	2011	Dobutamine, a member of this group, had 70% of the adrenaline (epinephrine) effect on arrestin via beta1-AR, but acted as a competitive antagonist of adrenaline via beta2-AR.	Dobutamine	0-10	adrenoceptor beta 2	Homo sapiens	165-173	
18253135-6	2008	Beta(2)-AR Gly16 homozygotes had a lower HR response during 5-30 microg kg(-1) min(-1) of the dobutamine infusion protocol compared to Arg16 carriers (P=0.03).	Dobutamine	94-104	adrenoceptor beta 2	Homo sapiens	0-10