PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22222157-1	2012	The present study was demonstrated to evaluate the effects of naturally occurring coumarins (NOCs) including simple coumarins, furanocoumarins, and pyranocoumarins on the inhibition of beta-secretase (BACE1) activity.	Coumarins	82-91	beta-secretase 1	Homo sapiens	201-206	
22222157-1	2012	The present study was demonstrated to evaluate the effects of naturally occurring coumarins (NOCs) including simple coumarins, furanocoumarins, and pyranocoumarins on the inhibition of beta-secretase (BACE1) activity.	Coumarins	116-125	beta-secretase 1	Homo sapiens	201-206	
22222157-2	2012	Of 41 NOCs examined, some furanocoumarins inhibited BACE1 activity, but simple coumarins and pyranocoumarins did not affect.	Coumarins	32-41	beta-secretase 1	Homo sapiens	52-57	
22222157-6	2012	The kinetics of inhibition of BACE1 by coumarins 24 was non-competitive inhibitors.	Coumarins	39-48	beta-secretase 1	Homo sapiens	30-35