PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26366750-4 2015 Our data revealed that total coumarins inhibited high glucose-induced HBZY-1 cell proliferation and hypertrophy, and produced its effects through downregulating transforming growth factor-beta1, connective tissue growth factor, and toll-like receptor 4 activation. Coumarins 29-38 cellular communication network factor 2 Rattus norvegicus 195-252 26366750-6 2015 Total coumarins, at a dose of 50 or 100 mg/kg: 1) significantly increased body weight; 2) ameliorated morphological evidence of renal pathology; 3) decreased blood levels of glucose and urea nitrogen; 4) decreased albuminuria and serum creatinine; and 5) reduced protein and gene levels of transforming growth factor-beta1, connective tissue growth factor, and toll-like receptor 4 in the kidneys. Coumarins 6-15 cellular communication network factor 2 Rattus norvegicus 324-381