PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24798733-4 2014 Chk2 localizes to kinetochores and is also required for Aurora B-serine 331 phosphorylation in nocodazole or unperturbed early prometaphase. Nocodazole 95-105 checkpoint kinase 2 Homo sapiens 0-4 20226795-7 2010 Mechanistically, fenofibrate treatment inhibited phosphorylation of checkpoint kinase Chk2 induced by nocodazole, and increased the expression of Wip1, a negative regulator of Chk2, suggesting that fenofibrate suppressed the nocodazole-induced G2/M cell cycle checkpoint through Wip1-mediated inhibition of Chk2 activation. Nocodazole 102-112 checkpoint kinase 2 Homo sapiens 86-90 17409144-8 2007 Importantly, we show that the direct interaction of EBNA3C with Chk2, the ATM/ATR signaling effector, is responsible for the release of this nocodazole-induced G2/M arrest and that this interaction leads to the serine 216 phosphorylation of Cdc25c, which is sequestered in the cytoplasm by 14-3-3. Nocodazole 141-151 checkpoint kinase 2 Homo sapiens 64-68 24764296-5 2014 In support, we found that nocodazole induced hMps1 phosphorylation at the previously identified CHK2 site Thr-288 and that this could be detected at the kinetochore in a CHK2-dependent manner. Nocodazole 26-36 checkpoint kinase 2 Homo sapiens 96-100 24764296-5 2014 In support, we found that nocodazole induced hMps1 phosphorylation at the previously identified CHK2 site Thr-288 and that this could be detected at the kinetochore in a CHK2-dependent manner. Nocodazole 26-36 checkpoint kinase 2 Homo sapiens 170-174