PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 660559-0 1978 Inhibition of dopamine beta-hydroxylase by 4-hydroxypyrazole: ethanol-pyrazole effects on serum dopamine beta-hydroxylase in vivo. 4-hydroxypyrazole 43-60 dopamine beta-hydroxylase Bos taurus 14-39 660559-3 1978 4-Hydroxypyrazole, the major metabolite of pyrazole, competitively inhibited both rat serum DBH and partially purified bovine adrenal DBH in vitro. 4-hydroxypyrazole 0-17 dopamine beta-hydroxylase Bos taurus 92-95 660559-3 1978 4-Hydroxypyrazole, the major metabolite of pyrazole, competitively inhibited both rat serum DBH and partially purified bovine adrenal DBH in vitro. 4-hydroxypyrazole 0-17 dopamine beta-hydroxylase Bos taurus 134-137 660559-4 1978 In vivo, 4-hydroxypyrazole caused large decreases in rat serum (53-84%) and adrenal (97%) DBH activity but had no effect on brain enzyme. 4-hydroxypyrazole 9-26 dopamine beta-hydroxylase Bos taurus 90-93 660559-5 1978 The decrease in rat serum DBH after chronic pyrazole treatment and the pyrazole-induced changes in physiological parameters, such as body weight and temperature, may be due to the formation of 4-hydroxypyrazole. 4-hydroxypyrazole 193-210 dopamine beta-hydroxylase Bos taurus 26-29