PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17093398-0	2006	Oxidative stress in pterygium: relationship between p53 and 8-hydroxydeoxyguanosine.	8-ohdg	60-83	tumor protein p53	Homo sapiens	52-55	
17093398-7	2006	To verify a possible significant association between p53 and 8-OHdG, we examined a series of 31 Ecuadorian pterygia for the expression of the two markers.	8-ohdg	61-67	tumor protein p53	Homo sapiens	53-56	
17093398-16	2006	All samples positive for p53 (11/31, 35.48%) were also positive for 8-OHdG immunostaining, and all specimens negative for 8-OHdG (10/31, 32.26%) were also negative for p53.	8-ohdg	68-74	tumor protein p53	Homo sapiens	25-28	
17093398-17	2006	When analyzed by Fisher"s exact test, 8-OHdG expression was significantly associated with p53 positivity (p=0.0049).	8-ohdg	38-44	tumor protein p53	Homo sapiens	90-93	
17093398-20	2006	CONCLUSIONS: Although pterygium is a lesion with limited local invasion and an inability to metastasize, the concomitant presence of altered p53 in 8-OHdG-immunoreactive cells could provide evidence of apparent genetic instability, which is in contrast to its benign clinical course.	8-ohdg	148-154	tumor protein p53	Homo sapiens	141-144	
15757539-2	2005	8-hydoxy-2deoxy-guanosine (8-OH-dG), a biomarker of oxidative DNA damage, plays important roles in initiation, progression, and prognosis of lung cancer, and closely relates with mutations of k-ras and p53 genes in carcinogenesis of lung tissue.	8-ohdg	27-34	tumor protein p53	Homo sapiens	202-205	
15757539-7	2005	Rank correlation analysis showed that protein expression of 8-OH-dG positively correlated with those of k-ras (RS=0.643, P < 0.01), and p53 (RS=0.827, P < 0.01)u protein expression of k-ras positively correlated with that of p53 (RS=0.897, P < 0.01).	8-ohdg	60-67	tumor protein p53	Homo sapiens	139-142	
15757539-7	2005	Rank correlation analysis showed that protein expression of 8-OH-dG positively correlated with those of k-ras (RS=0.643, P < 0.01), and p53 (RS=0.827, P < 0.01)u protein expression of k-ras positively correlated with that of p53 (RS=0.897, P < 0.01).	8-ohdg	60-67	tumor protein p53	Homo sapiens	231-234	
15342409-4	2004	Using synthetic DNA containing 8-oxo-7,8-dihydro-2"-deoxyguanosine (8-oxoG), we showed that p53 was pulled down together with two BER proteins, human 8-oxoguanine glycosylase (hOGG1) and AP endonuclease (APE).	8-ohdg	31-66	tumor protein p53	Homo sapiens	92-95	
15342409-4	2004	Using synthetic DNA containing 8-oxo-7,8-dihydro-2"-deoxyguanosine (8-oxoG), we showed that p53 was pulled down together with two BER proteins, human 8-oxoguanine glycosylase (hOGG1) and AP endonuclease (APE).	8-ohdg	68-74	tumor protein p53	Homo sapiens	92-95	
27260513-0	2016	8-Oxo-7,8-dihydro-2"-deoxyguanosine and other lesions along the coding strand of the exon 5 of the tumour suppressor gene P53 in a breast cancer case-control study.	8-ohdg	0-35	tumor protein p53	Homo sapiens	122-125	
27260513-3	2016	We detected a significant "in vitro" generation of 8-oxodG between the codons 163 and 175, corresponding to a TP53 region with high mutation prevalence, after treatment with xanthine plus xanthine oxidase, a ROS-generating system.	8-ohdg	51-58	tumor protein p53	Homo sapiens	110-114	
18489080-0	2008	The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance.	8-ohdg	67-77	tumor protein p53	Homo sapiens	15-18	
18489080-7	2008	An RP-HPLC-ECD assay was used to detect the formation of 8-oxo-dGuo in p53 cDNA exposed to representative quinones, BP-7,8-dione, BA-3,4-dione, and DMBA-3,4-dione under redox cycling conditions.	8-ohdg	57-67	tumor protein p53	Homo sapiens	71-74	
18489080-10	2008	By contrast, micromolar concentrations of (+/-)- anti-BPDE generated (+)- trans- anti-BPDE-N (2)-dGuo adducts (detected by stable-isotope dilution LC/MS methodology) in p53 cDNA that correlated in a linear fashion with mutagenic frequency, but no 8-oxo-dGuo was detected.	8-ohdg	247-257	tumor protein p53	Homo sapiens	169-172	
32942546-4	2020	Results indicated a significant 130% excess of 8-oxodG at -TGC- position of p53 codon 176 in HCV-HCC cases as compared to controls, after correction for age and gender, whereas a not significant increment of 5-OHC at -TGC- position was found.	8-ohdg	47-54	tumor protein p53	Homo sapiens	76-79	
17567683-8	2007	Inhibition of p53 resulted in excessive oxidation of DNA; control SiHa cells exhibited a more rapid removal of 8-oxo-7,8-dihydro-2"-deoxyguanosine from DNA compared with p53-deficient SiHa cells exposed to the same level of H2O2 challenge.	8-ohdg	111-146	tumor protein p53	Homo sapiens	14-17