PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9794919-3 1998 Mrp2, the apical isoform of the multidrug resistance protein, alternatively termed canalicular Mrp (cMrp) or canalicular multispecific organic anion transporter (cMoat), is a 190-kd membrane glycoprotein mediating adenosine triphosphate (ATP)-dependent transport of glucuronides, glutathione S-conjugates, and other amphiphilic anions across the hepatocyte canalicular membrane into bile. Glucuronides 266-278 ATP binding cassette subfamily C member 2 Homo sapiens 0-4 9794919-3 1998 Mrp2, the apical isoform of the multidrug resistance protein, alternatively termed canalicular Mrp (cMrp) or canalicular multispecific organic anion transporter (cMoat), is a 190-kd membrane glycoprotein mediating adenosine triphosphate (ATP)-dependent transport of glucuronides, glutathione S-conjugates, and other amphiphilic anions across the hepatocyte canalicular membrane into bile. Glucuronides 266-278 ATP binding cassette subfamily C member 2 Homo sapiens 100-104 9794919-3 1998 Mrp2, the apical isoform of the multidrug resistance protein, alternatively termed canalicular Mrp (cMrp) or canalicular multispecific organic anion transporter (cMoat), is a 190-kd membrane glycoprotein mediating adenosine triphosphate (ATP)-dependent transport of glucuronides, glutathione S-conjugates, and other amphiphilic anions across the hepatocyte canalicular membrane into bile. Glucuronides 266-278 ATP binding cassette subfamily C member 2 Homo sapiens 109-160 9794919-3 1998 Mrp2, the apical isoform of the multidrug resistance protein, alternatively termed canalicular Mrp (cMrp) or canalicular multispecific organic anion transporter (cMoat), is a 190-kd membrane glycoprotein mediating adenosine triphosphate (ATP)-dependent transport of glucuronides, glutathione S-conjugates, and other amphiphilic anions across the hepatocyte canalicular membrane into bile. Glucuronides 266-278 ATP binding cassette subfamily C member 2 Homo sapiens 162-167 9355767-0 1997 ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Glucuronides 37-49 ATP binding cassette subfamily C member 2 Homo sapiens 130-134 9355767-2 1997 We demonstrate for the first time that ATP-dependent transport of both bilirubin glucuronides is mediated by the multidrug resistance protein (MRP1) as well as by the distinct canalicular (apical) isoform MRP2, also termed cMRP or cMOAT (canalicular multispecific organic anion transporter). Glucuronides 81-93 ATP binding cassette subfamily C member 2 Homo sapiens 205-209 9355767-2 1997 We demonstrate for the first time that ATP-dependent transport of both bilirubin glucuronides is mediated by the multidrug resistance protein (MRP1) as well as by the distinct canalicular (apical) isoform MRP2, also termed cMRP or cMOAT (canalicular multispecific organic anion transporter). Glucuronides 81-93 ATP binding cassette subfamily C member 2 Homo sapiens 223-227 9355767-2 1997 We demonstrate for the first time that ATP-dependent transport of both bilirubin glucuronides is mediated by the multidrug resistance protein (MRP1) as well as by the distinct canalicular (apical) isoform MRP2, also termed cMRP or cMOAT (canalicular multispecific organic anion transporter). Glucuronides 81-93 ATP binding cassette subfamily C member 2 Homo sapiens 231-236 9355767-2 1997 We demonstrate for the first time that ATP-dependent transport of both bilirubin glucuronides is mediated by the multidrug resistance protein (MRP1) as well as by the distinct canalicular (apical) isoform MRP2, also termed cMRP or cMOAT (canalicular multispecific organic anion transporter). Glucuronides 81-93 ATP binding cassette subfamily C member 2 Homo sapiens 238-289 34169529-8 2021 There were significant associations of pharmacokinetic parameters with ABCC2 haplotypes for mycophenolic acid clearance (L/hr), mycophenolic acid AUC0-12h (mg hr/L) and the ratio of mycophenolic acid glucuronide to mycophenolic acid AUC0-12h . Glucuronides 200-211 ATP binding cassette subfamily C member 2 Homo sapiens 71-76 9377473-0 1997 Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2. Glucuronides 40-52 ATP binding cassette subfamily C member 2 Homo sapiens 99-103 34862251-11 2021 Considering the significant role of MRP3/Mrp3 and MRP2/Mrp2 in the excretion of glucuronides, the competition between them for M5 was possibly the determinant for the different excretion routes in humans and rats. Glucuronides 80-92 ATP binding cassette subfamily C member 2 Homo sapiens 50-54 34862251-11 2021 Considering the significant role of MRP3/Mrp3 and MRP2/Mrp2 in the excretion of glucuronides, the competition between them for M5 was possibly the determinant for the different excretion routes in humans and rats. Glucuronides 80-92 ATP binding cassette subfamily C member 2 Homo sapiens 55-59 34169529-9 2021 The wildtype haplotype ABCC2 CGC had greater mycophenolic acid AUC0-12h (P = 0.017), slower clearance (P = 0.013) and lower mycophenolic acid glucuronide to mycophenolic acid AUC0-12h ratio (P = 0.047) compared to the reduced function ABCC2 haplotype, CGT. Glucuronides 142-153 ATP binding cassette subfamily C member 2 Homo sapiens 23-28 34554580-6 2022 By combining these strategies, we illustrate that the role of P-gp in moxifloxacin transport is limited and implicate MRP2 as transporter of moxifloxacin-glucuronide followed by rapid hydrolysis in the gut. Glucuronides 154-165 ATP binding cassette subfamily C member 2 Homo sapiens 118-122 30959153-0 2019 Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney. Glucuronides 6-17 ATP binding cassette subfamily C member 2 Homo sapiens 75-79 31704245-8 2020 Of these transporters, only MRP2 and MRP3 transported the androgen glucuronides investigated. Glucuronides 67-79 ATP binding cassette subfamily C member 2 Homo sapiens 28-32 31704245-10 2020 MRP2 transported the glucuronides at lower affinity, as indicated by Km values over 100 muM. Glucuronides 21-33 ATP binding cassette subfamily C member 2 Homo sapiens 0-4 31704245-13 2020 Our results explain the transporter-mediated disposition of androgen glucuronides in humans, and shed light on differences between the human efflux transporters MRP2, MRP3, MRP4, BCRP and MDR1. Glucuronides 69-81 ATP binding cassette subfamily C member 2 Homo sapiens 161-165 30959153-9 2019 The glucuronides of inactive androgens, AG and EtioG were preferentially transported by MRP3, whereas the glucuronides of active androgens, TG and DHTG were mainly transported by MRP2 in liver. Glucuronides 106-118 ATP binding cassette subfamily C member 2 Homo sapiens 179-183 30959153-12 2019 In kidney, all studied glucuronides seemed to be preferentially effluxed by MRP2 and MDR1 (for EtioG). Glucuronides 23-35 ATP binding cassette subfamily C member 2 Homo sapiens 76-80 26659924-7 2016 The present results support that the glucuronides of NSAIDs, as well as the parent NSAIDs, are involved in the inhibition of urinary excretion of MTX via MRP2 and MRP4. Glucuronides 37-49 ATP binding cassette subfamily C member 2 Homo sapiens 154-158 26500117-3 2016 Mrp-2 is an adenosine triphosphate (ATP)-binding cassette transporter that plays an important role in detoxification and chemoprotection by transporting a wide range of compounds, especially conjugates of lipophilic substances with glutathione, organic anions, and drug metabolites such as glucuronides. Glucuronides 290-302 ATP binding cassette subfamily C member 2 Homo sapiens 0-5 29175180-0 2018 Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP. Glucuronides 29-41 ATP binding cassette subfamily C member 2 Homo sapiens 51-55 28850245-10 2017 The transport activity of MRP2 with all of the studied small glucuronides was relatively very low, even though it transported the reference compound, estradiol-17beta-glucuronide, at a high rate (Vmax = 3500 pmol/mg/min). Glucuronides 61-73 ATP binding cassette subfamily C member 2 Homo sapiens 26-30 22982073-8 2012 MK-571, chemical inhibitor of MRP2, MRP3, and MRP4, significantly reduced the efflux of glucuronide in the apical-to-basolateral (A-B) and B-A directions in a dose-dependent manner. Glucuronides 88-99 ATP binding cassette subfamily C member 2 Homo sapiens 30-34 23462933-10 2013 The glucuronide, sulfate, and GSH conjugates are excreted by transporters in the canalicular (Mrp2 and Bcrp) and basolateral (Mrp3 and Mrp4) hepatocyte membranes. Glucuronides 4-15 ATP binding cassette subfamily C member 2 Homo sapiens 94-98 23387445-8 2013 Additionally, a direct glucuronide of bosentan could be identified intracellularly in cell lines expressing UGT1A1 and in the apical compartments of cell lines expressing UGT1A1 and MRP2. Glucuronides 23-34 ATP binding cassette subfamily C member 2 Homo sapiens 182-186 25204339-9 2014 Since OATP1B1/1B3 are known to be involved in hepatic uptake of circulating bilirubin glucuronides, inhibition of OATP1B1/1B3 and MRP2 may underlie isolated increases in conjugated bilirubin. Glucuronides 86-98 ATP binding cassette subfamily C member 2 Homo sapiens 130-134 23750830-4 2013 Eventually, the glucuronide metabolite is excreted into the bile via MRP2. Glucuronides 16-27 ATP binding cassette subfamily C member 2 Homo sapiens 69-73 25400909-3 2012 These glucuronides and sulfates are subsequently excreted via ABC transporters (e.g., MRP2 or BCRP). Glucuronides 6-18 ATP binding cassette subfamily C member 2 Homo sapiens 86-90 22683417-2 2012 The aim of our study was to identify transporters involved in the efflux of raloxifene and its glucuronide metabolites by various in vitro models and by an in vivo study to explore the possible involvement of P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP)1, MRP2, MRP3, and breast cancer resistance protein in the observed high interindividual variability. Glucuronides 95-106 ATP binding cassette subfamily C member 2 Homo sapiens 279-283 22245901-1 2012 BACKGROUND & AIMS: Multidrug resistance-associated protein 2 (in humans, MRP2; in rodents, Mrp2) mediates biliary excretion of bilirubin glucuronides. Glucuronides 141-153 ATP binding cassette subfamily C member 2 Homo sapiens 23-64 22245901-1 2012 BACKGROUND & AIMS: Multidrug resistance-associated protein 2 (in humans, MRP2; in rodents, Mrp2) mediates biliary excretion of bilirubin glucuronides. Glucuronides 141-153 ATP binding cassette subfamily C member 2 Homo sapiens 77-81 22245901-1 2012 BACKGROUND & AIMS: Multidrug resistance-associated protein 2 (in humans, MRP2; in rodents, Mrp2) mediates biliary excretion of bilirubin glucuronides. Glucuronides 141-153 ATP binding cassette subfamily C member 2 Homo sapiens 95-99 21687948-4 2011 Polymorphisms of MRP2, a protein involved in methotrexate, cisplatin and irinotecan active metabolite glucuronide transport, negatively affect platinum-based chemotherapy response. Glucuronides 102-113 ATP binding cassette subfamily C member 2 Homo sapiens 17-21 21923755-10 2012 Moreover, etoposide and possibly also its glucuronide are substrates of MRP2. Glucuronides 42-53 ATP binding cassette subfamily C member 2 Homo sapiens 72-76 21860343-2 2011 The main metabolite of MPA, MPA glucuronide is actively secreted into the bile via the multidrug resistance-associated protein 2 (MRP2) transporter. Glucuronides 32-43 ATP binding cassette subfamily C member 2 Homo sapiens 87-128 21860343-2 2011 The main metabolite of MPA, MPA glucuronide is actively secreted into the bile via the multidrug resistance-associated protein 2 (MRP2) transporter. Glucuronides 32-43 ATP binding cassette subfamily C member 2 Homo sapiens 130-134 20082599-3 2010 Although ABCC2/Abcc2 transports a variety of amphiphilic anions that belong to different classes of molecules, such as endogenous compounds (e.g., bilirubin-glucuronides), drugs, toxic chemicals, nutraceuticals, and their conjugates, it displays a preference for phase II conjugates. Glucuronides 157-169 ATP binding cassette subfamily C member 2 Homo sapiens 9-14 21691255-1 2011 BACKGROUND: Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide, and sulfate conjugates of endobiotics and xenobiotics. Glucuronides 115-126 ATP binding cassette subfamily C member 2 Homo sapiens 12-53 21691255-1 2011 BACKGROUND: Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide, and sulfate conjugates of endobiotics and xenobiotics. Glucuronides 115-126 ATP binding cassette subfamily C member 2 Homo sapiens 55-59 21691255-1 2011 BACKGROUND: Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide, and sulfate conjugates of endobiotics and xenobiotics. Glucuronides 115-126 ATP binding cassette subfamily C member 2 Homo sapiens 61-66 20082599-3 2010 Although ABCC2/Abcc2 transports a variety of amphiphilic anions that belong to different classes of molecules, such as endogenous compounds (e.g., bilirubin-glucuronides), drugs, toxic chemicals, nutraceuticals, and their conjugates, it displays a preference for phase II conjugates. Glucuronides 157-169 ATP binding cassette subfamily C member 2 Homo sapiens 15-20 18460254-6 2008 The defect is due to the absence of the canalicular protein MRP2 located on chromosomes 10q 24, which is responsible for the transport of biliary glucuronides and related organic anions into bile. Glucuronides 146-158 ATP binding cassette subfamily C member 2 Homo sapiens 60-64 19566819-6 2010 Unlike MRP1, MRP2 functions in the extrusion of endogenous organic anions, such as bilirubin glucuronide and certain anticancer agents. Glucuronides 93-104 ATP binding cassette subfamily C member 2 Homo sapiens 13-17 19588995-1 2009 Human ATP-binding cassette (ABC) transporter ABCC2 (cMOAT/MRP2) plays a crucial role in the hepatobiliary transport of sulfate-, glucuronide-, and glutathione-conjugated metabolites as well as a variety of amphiphilic organic anions derived from hepatic metabolism. Glucuronides 129-140 ATP binding cassette subfamily C member 2 Homo sapiens 45-50 19588995-1 2009 Human ATP-binding cassette (ABC) transporter ABCC2 (cMOAT/MRP2) plays a crucial role in the hepatobiliary transport of sulfate-, glucuronide-, and glutathione-conjugated metabolites as well as a variety of amphiphilic organic anions derived from hepatic metabolism. Glucuronides 129-140 ATP binding cassette subfamily C member 2 Homo sapiens 52-57 19588995-1 2009 Human ATP-binding cassette (ABC) transporter ABCC2 (cMOAT/MRP2) plays a crucial role in the hepatobiliary transport of sulfate-, glucuronide-, and glutathione-conjugated metabolites as well as a variety of amphiphilic organic anions derived from hepatic metabolism. Glucuronides 129-140 ATP binding cassette subfamily C member 2 Homo sapiens 58-62 18597651-4 2008 RESULTS: Multivariate analyses indicate that the ABCC2 -24T promoter polymorphism is associated with a 25% increase in acyl mycophenolic acid phenolic glucuronide level. Glucuronides 151-162 ATP binding cassette subfamily C member 2 Homo sapiens 49-54 14643890-2 2004 ABCC1 (MRP1), ABCC2 (MRP2) and ABCC3 (MRP3) are all able to facilitate the efflux of anionic conjugates including glutathione (GSH), glucuronide and sulfate conjugates of xenobiotics and endogenous molecules. Glucuronides 133-144 ATP binding cassette subfamily C member 2 Homo sapiens 14-19 17828742-1 2007 The lipid lowering agent ezetimibe (EZ) and its intestinally formed glucuronide (GLUC) were shown to be substrates of the efflux transporters P-glycoprotein (P-gp) and the multidrug resistance associated protein 2 (MRP2) which markedly influences the disposition and efficacy of EZ in man. Glucuronides 68-79 ATP binding cassette subfamily C member 2 Homo sapiens 172-213 17828742-1 2007 The lipid lowering agent ezetimibe (EZ) and its intestinally formed glucuronide (GLUC) were shown to be substrates of the efflux transporters P-glycoprotein (P-gp) and the multidrug resistance associated protein 2 (MRP2) which markedly influences the disposition and efficacy of EZ in man. Glucuronides 68-79 ATP binding cassette subfamily C member 2 Homo sapiens 215-219 17578901-11 2007 Inhibition of renal uptake (via OAT3) and efflux processes (via MRP2 and MRP4) explains the possible sites of drug-drug interaction for methotrexate with probenecid and some NSAIDs, including their glucuronides. Glucuronides 198-210 ATP binding cassette subfamily C member 2 Homo sapiens 64-68 17108237-1 2007 The multidrug resistance protein 2 (MRP2/ABCC2) mediates the biliary excretion of glucuronide and glutathione conjugates of endogenous and exogenous compounds. Glucuronides 82-93 ATP binding cassette subfamily C member 2 Homo sapiens 36-40 17108237-1 2007 The multidrug resistance protein 2 (MRP2/ABCC2) mediates the biliary excretion of glucuronide and glutathione conjugates of endogenous and exogenous compounds. Glucuronides 82-93 ATP binding cassette subfamily C member 2 Homo sapiens 41-46 15795089-0 2005 Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites. Glucuronides 120-131 ATP binding cassette subfamily C member 2 Homo sapiens 94-98 17227625-0 2007 Efflux of baicalin, a flavone glucuronide of Scutellariae Radix, on Caco-2 cells through multidrug resistance-associated protein 2. Glucuronides 30-41 ATP binding cassette subfamily C member 2 Homo sapiens 89-130 16842856-8 2006 Observations from clinical and experimental studies have defined key events in the pathogenesis of these drugs, including roles for multidrug resistance-associated protein 2 (MRP2) and other transporters in biliary secretion and adduction of enterocyte proteins by reactive acyl glucuronide metabolites as a likely mechanism for intestinal injury. Glucuronides 279-290 ATP binding cassette subfamily C member 2 Homo sapiens 132-173 16842856-8 2006 Observations from clinical and experimental studies have defined key events in the pathogenesis of these drugs, including roles for multidrug resistance-associated protein 2 (MRP2) and other transporters in biliary secretion and adduction of enterocyte proteins by reactive acyl glucuronide metabolites as a likely mechanism for intestinal injury. Glucuronides 279-290 ATP binding cassette subfamily C member 2 Homo sapiens 175-179 15846474-1 2005 PURPOSE: Multidrug resistance-associated protein 2 (MRP2/ABCC2) is predominantly expressed in the liver canalicular membrane and plays an important role in the biliary excretion of organic anions including glucuronide and glutathione conjugates. Glucuronides 206-217 ATP binding cassette subfamily C member 2 Homo sapiens 9-50 15846474-1 2005 PURPOSE: Multidrug resistance-associated protein 2 (MRP2/ABCC2) is predominantly expressed in the liver canalicular membrane and plays an important role in the biliary excretion of organic anions including glucuronide and glutathione conjugates. Glucuronides 206-217 ATP binding cassette subfamily C member 2 Homo sapiens 52-56 15846474-1 2005 PURPOSE: Multidrug resistance-associated protein 2 (MRP2/ABCC2) is predominantly expressed in the liver canalicular membrane and plays an important role in the biliary excretion of organic anions including glucuronide and glutathione conjugates. Glucuronides 206-217 ATP binding cassette subfamily C member 2 Homo sapiens 57-62 14643890-2 2004 ABCC1 (MRP1), ABCC2 (MRP2) and ABCC3 (MRP3) are all able to facilitate the efflux of anionic conjugates including glutathione (GSH), glucuronide and sulfate conjugates of xenobiotics and endogenous molecules. Glucuronides 133-144 ATP binding cassette subfamily C member 2 Homo sapiens 21-25 12483266-5 2002 Amidated bile acids are excreted into bile by bile salt export pump (BSEP), and organic anions and bile acid sulfates and glucuronides are excreted by multidrug resistance protein 2 (MRP2). Glucuronides 122-134 ATP binding cassette subfamily C member 2 Homo sapiens 151-181 12524417-4 2003 Immunostaining for the canalicular transporter, multidrug resistant protein 2 (MRP2), responsible for biliary secretion of several organic anions including bilirubin glucuronides, showed sustained expression in both biopsies as well as relocalisation with appearance of strong staining of the basolateral membrane of the hepatocyte. Glucuronides 166-178 ATP binding cassette subfamily C member 2 Homo sapiens 79-83 12395335-8 2002 Vanadate-induced nucleotide trapping with 8-azido-[alpha-32P]ATP in the wild-type MRP2 was stimulated by estradiol glucuronide (E(2)17betaG) in a concentration-dependent manner but that in the Q1382R MRP2 was not. Glucuronides 115-126 ATP binding cassette subfamily C member 2 Homo sapiens 82-86 12395335-8 2002 Vanadate-induced nucleotide trapping with 8-azido-[alpha-32P]ATP in the wild-type MRP2 was stimulated by estradiol glucuronide (E(2)17betaG) in a concentration-dependent manner but that in the Q1382R MRP2 was not. Glucuronides 115-126 ATP binding cassette subfamily C member 2 Homo sapiens 200-204 12130697-1 2002 The multidrug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter accepting a diverse range of substrates, including glutathione, glucuronide, and sulfate conjugates of many endo- and xenobiotics. Glucuronides 152-163 ATP binding cassette subfamily C member 2 Homo sapiens 4-34 12130697-1 2002 The multidrug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter accepting a diverse range of substrates, including glutathione, glucuronide, and sulfate conjugates of many endo- and xenobiotics. Glucuronides 152-163 ATP binding cassette subfamily C member 2 Homo sapiens 36-40 12130697-1 2002 The multidrug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter accepting a diverse range of substrates, including glutathione, glucuronide, and sulfate conjugates of many endo- and xenobiotics. Glucuronides 152-163 ATP binding cassette subfamily C member 2 Homo sapiens 42-47 12483266-5 2002 Amidated bile acids are excreted into bile by bile salt export pump (BSEP), and organic anions and bile acid sulfates and glucuronides are excreted by multidrug resistance protein 2 (MRP2). Glucuronides 122-134 ATP binding cassette subfamily C member 2 Homo sapiens 183-187 11124235-0 2001 Correction to "Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan" Glucuronides 111-122 ATP binding cassette subfamily C member 2 Homo sapiens 20-25 11124235-0 2001 Correction to "Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan" Glucuronides 111-122 ATP binding cassette subfamily C member 2 Homo sapiens 26-30 10944550-10 2000 MRP2 is the major transporter responsible for the secretion of bilirubin glucuronides into bile, and humans without MRP2 develop a mild liver disease known as the Dubin-Johnson syndrome. Glucuronides 73-85 ATP binding cassette subfamily C member 2 Homo sapiens 0-4 11023036-8 2000 (3) Transport mechanism of bilirubin glucuronides across the hepatocyte canalicular membrane: at the canalicular membrane, bilirubin glucuronides are excreted into bile by multidrug resistance-associated protein 2 (MRP2), a member of the ATP-binding cassette transporter family. Glucuronides 37-49 ATP binding cassette subfamily C member 2 Homo sapiens 172-213 11023036-8 2000 (3) Transport mechanism of bilirubin glucuronides across the hepatocyte canalicular membrane: at the canalicular membrane, bilirubin glucuronides are excreted into bile by multidrug resistance-associated protein 2 (MRP2), a member of the ATP-binding cassette transporter family. Glucuronides 37-49 ATP binding cassette subfamily C member 2 Homo sapiens 215-219 11023036-8 2000 (3) Transport mechanism of bilirubin glucuronides across the hepatocyte canalicular membrane: at the canalicular membrane, bilirubin glucuronides are excreted into bile by multidrug resistance-associated protein 2 (MRP2), a member of the ATP-binding cassette transporter family. Glucuronides 133-145 ATP binding cassette subfamily C member 2 Homo sapiens 172-213 11023036-8 2000 (3) Transport mechanism of bilirubin glucuronides across the hepatocyte canalicular membrane: at the canalicular membrane, bilirubin glucuronides are excreted into bile by multidrug resistance-associated protein 2 (MRP2), a member of the ATP-binding cassette transporter family. Glucuronides 133-145 ATP binding cassette subfamily C member 2 Homo sapiens 215-219