PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20606004-6 2010 In vitro biliary excretion of micafungin was reduced by 80 and 75% in the presence of the bile salt export pump (BSEP) inhibitors taurocholate (100 muM) and nefazodone (25 muM), respectively. Taurocholic Acid 130-142 latexin Homo sapiens 148-151 27676153-4 2016 Fusidic acid demonstrated concentration-dependent inhibition of human NTCP- and BSEP-mediated taurocholic acid transport with IC50 values of 44 and 3.8 muM, respectively. Taurocholic Acid 94-110 latexin Homo sapiens 152-155 27013400-9 2016 Co-incubation with increasing tolvaptan concentrations (0.15-50 muM) decreased TCA (2.5 muM) cell+bile accumulation and the TCA biliary excretion index (BEI; from 76% to 51%), consistent with inhibition of the bile salt export pump (BSEP). Taurocholic Acid 79-82 latexin Homo sapiens 64-67 26952880-6 2016 CsA (10 muM) was cytotoxic toward HepaRG cells in the presence of BAs and also reduced the biliary efflux rate of [(3)H]taurocholic acid from 38.5% to 19.2%. Taurocholic Acid 120-136 latexin Homo sapiens 8-11 24780196-7 2014 RESULTS: ERp29 expression and the apoptotic index were significantly increased in HTR-8/SVneo cells exposed to 100 muM TCA; so were p-p38 and caspase-3 activity, compared with the 50 muM, 10 muM TCA groups and negative control group (P < 0.05, respectively). Taurocholic Acid 119-122 latexin Homo sapiens 115-118 24780196-7 2014 RESULTS: ERp29 expression and the apoptotic index were significantly increased in HTR-8/SVneo cells exposed to 100 muM TCA; so were p-p38 and caspase-3 activity, compared with the 50 muM, 10 muM TCA groups and negative control group (P < 0.05, respectively). Taurocholic Acid 119-122 latexin Homo sapiens 183-186 24780196-7 2014 RESULTS: ERp29 expression and the apoptotic index were significantly increased in HTR-8/SVneo cells exposed to 100 muM TCA; so were p-p38 and caspase-3 activity, compared with the 50 muM, 10 muM TCA groups and negative control group (P < 0.05, respectively). Taurocholic Acid 119-122 latexin Homo sapiens 183-186 20606004-4 2010 Micafungin uptake into hepatocytes was inhibited by taurocholate (K(i) = 61 muM), Na(+) depletion (45-55% reduced), and 10 muM rifampin (20-25% reduced); these observations support the involvement of Na(+)-taurocholate-cotransporting polypeptide (NTCP/Ntcp) and, to a lesser extent, organic anion-transporting polypeptides in the hepatic uptake of micafungin. Taurocholic Acid 52-64 latexin Homo sapiens 76-79 26507107-8 2016 The biliary clearance of taurocholic acid (TCA) decreased by 43% when SCHH were co-incubated with tolvaptan (15 muM) and TCA (2.5 muM). Taurocholic Acid 25-41 latexin Homo sapiens 112-115 26507107-8 2016 The biliary clearance of taurocholic acid (TCA) decreased by 43% when SCHH were co-incubated with tolvaptan (15 muM) and TCA (2.5 muM). Taurocholic Acid 25-41 latexin Homo sapiens 130-133 26507107-8 2016 The biliary clearance of taurocholic acid (TCA) decreased by 43% when SCHH were co-incubated with tolvaptan (15 muM) and TCA (2.5 muM). Taurocholic Acid 43-46 latexin Homo sapiens 112-115 26507107-8 2016 The biliary clearance of taurocholic acid (TCA) decreased by 43% when SCHH were co-incubated with tolvaptan (15 muM) and TCA (2.5 muM). Taurocholic Acid 43-46 latexin Homo sapiens 130-133 26507107-8 2016 The biliary clearance of taurocholic acid (TCA) decreased by 43% when SCHH were co-incubated with tolvaptan (15 muM) and TCA (2.5 muM). Taurocholic Acid 121-124 latexin Homo sapiens 130-133