PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26999807-2 2016 The nonhepatotoxic bile acid taurocholate activates Akt and Erk through the sphingosine-1-phosphate receptor 2 (S1PR2). Taurocholic Acid 29-41 AKT serine/threonine kinase 1 Homo sapiens 52-55 26518876-9 2015 Inhibition of S1PR2 activation with chemical antagonist (JTE-013) or down-regulation of S1PR2 expression with gene-specific shRNA not only reduced COX-2 expression, but also inhibited TCA-induced activation of EGFR and the ERK1/2/Akt-NF-kappaB signaling cascade. Taurocholic Acid 184-187 AKT serine/threonine kinase 1 Homo sapiens 230-233