PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23255551-6 2013 Further study on other Oatp1a2 substrates showed that the high affinity component for E-3-S is responsible for the interaction with taurocholate, bromsulphthalein, and rifampicin and is sensitive to proton concentration change, whereas the low affinity binding site is only involved in the binding of the antitumor drug methotrexate and had no response to change of pH. Taurocholic Acid 132-144 solute carrier organic anion transporter family member 1A2 Homo sapiens 23-30 24970118-0 2014 Molecular regulation of organic anion transporting polypeptide 1A2 (OATP1A2)by taurocholic acid in Bewo Cells. Taurocholic Acid 79-95 solute carrier organic anion transporter family member 1A2 Homo sapiens 68-75 24970118-1 2014 To characterize the mechanisms of action of taurocholic acid(TCA) and farnesoid X receptor(FXR) on organic anion transporting polypeptide 1A2(OATP1A2) expression in placental Bewo cell line. Taurocholic Acid 44-60 solute carrier organic anion transporter family member 1A2 Homo sapiens 142-149 9334206-1 1997 Organic anion transporting polypeptide (oatp) is an integral membrane protein cloned from rat liver that mediates Na+-independent transport of organic anions such as sulfobromophthalein and taurocholic acid. Taurocholic Acid 190-206 solute carrier organic anion transporter family member 1A2 Homo sapiens 40-44 19027771-5 2009 MC transport was tested by exposing mWBCs to three different MC-congeners (MC-LR, -LW, -LF) with/without co-incubation with the OATP/Oatp-substrates taurocholate (TC) and bromosulfophthalein (BSP). Taurocholic Acid 149-161 solute carrier organic anion transporter family member 1A2 Homo sapiens 133-137 15737679-6 2005 This microcystin-LR transport was inhibited by co-incubation with the known Oatp/OATP substrates taurocholate (TC) and bromosulfophthalein (BSP). Taurocholic Acid 97-109 solute carrier organic anion transporter family member 1A2 Homo sapiens 76-80 15737679-6 2005 This microcystin-LR transport was inhibited by co-incubation with the known Oatp/OATP substrates taurocholate (TC) and bromosulfophthalein (BSP). Taurocholic Acid 97-109 solute carrier organic anion transporter family member 1A2 Homo sapiens 81-85 15737679-6 2005 This microcystin-LR transport was inhibited by co-incubation with the known Oatp/OATP substrates taurocholate (TC) and bromosulfophthalein (BSP). Taurocholic Acid 111-113 solute carrier organic anion transporter family member 1A2 Homo sapiens 76-80 15737679-6 2005 This microcystin-LR transport was inhibited by co-incubation with the known Oatp/OATP substrates taurocholate (TC) and bromosulfophthalein (BSP). Taurocholic Acid 111-113 solute carrier organic anion transporter family member 1A2 Homo sapiens 81-85 12542534-8 2003 Using a newly developed uptake-transport assay, uptake of known and well-characterized OATP substrates like estradiol-17beta-glucuronide and estrone sulfate was inhibited in normal human epidermal keratinocytes by specific inhibitors such as taurocholate, verifying the functional capacity of the expressed OATPs. Taurocholic Acid 242-254 solute carrier organic anion transporter family member 1A2 Homo sapiens 87-91 11230727-3 2001 Expression of the apical sodium-dependent bile acid transporter (ASBT) and of the organic anion transporting polypeptide (OATP-A) was detected and associated with sodium-dependent and sodium-independent [(3)H]taurocholate uptake in BEC. Taurocholic Acid 209-221 solute carrier organic anion transporter family member 1A2 Homo sapiens 122-128 9334206-12 1997 These data indicate that oatp-mediated taurocholate transport is Na+-independent, saturable, and accompanied by HCO3- exchange. Taurocholic Acid 39-51 solute carrier organic anion transporter family member 1A2 Homo sapiens 25-29 9328325-9 1997 The up-regulation of OATP expression by taurocholate could serve to enhance the sinusoidal efflux of toxic intracellular compounds during chronic cholestasis. Taurocholic Acid 40-52 solute carrier organic anion transporter family member 1A2 Homo sapiens 21-25 8621133-4 1996 Uptake of [3H]-taurocholic acid was saturable and entirely Na+ independent, with the kinetic characteristics of the human liver organic anion transporting polypeptide (OATP). Taurocholic Acid 15-31 solute carrier organic anion transporter family member 1A2 Homo sapiens 128-166 8621133-4 1996 Uptake of [3H]-taurocholic acid was saturable and entirely Na+ independent, with the kinetic characteristics of the human liver organic anion transporting polypeptide (OATP). Taurocholic Acid 15-31 solute carrier organic anion transporter family member 1A2 Homo sapiens 168-172 8779893-10 1996 HeLa cell monolayers transfected with the oatp cDNA transported tracer BSP and taurocholate at rates substantially higher than monolayers transfected with a control plasmid. Taurocholic Acid 79-91 solute carrier organic anion transporter family member 1A2 Homo sapiens 42-46 8779894-2 1996 The so-called "organic anion-transporting polypeptide" (i.e., oatp) has a number of known substrates, including bromosulfophthalein (BSP) and taurocholic acid (TCA) (E. Jacquemin, B. Hagenbuch, B. Stieger, A. W. Wolkoff, and P. J. Meier. Taurocholic Acid 142-158 solute carrier organic anion transporter family member 1A2 Homo sapiens 62-66 8779894-2 1996 The so-called "organic anion-transporting polypeptide" (i.e., oatp) has a number of known substrates, including bromosulfophthalein (BSP) and taurocholic acid (TCA) (E. Jacquemin, B. Hagenbuch, B. Stieger, A. W. Wolkoff, and P. J. Meier. Taurocholic Acid 160-163 solute carrier organic anion transporter family member 1A2 Homo sapiens 62-66 8779894-11 1996 The affinity of oatp for [3H]E2-17G was significantly higher than that for TCA (K(m) of 3 microM vs. 27 microM, respectively). Taurocholic Acid 75-78 solute carrier organic anion transporter family member 1A2 Homo sapiens 16-20