PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15638994-8 2005 In addition, digoxin and taurocholate, substrates for organic anion transporting polypeptide subtype 2 (Oatp2), significantly inhibited [(3)H]PGE(1) uptake. Taurocholic Acid 25-37 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 54-102 15638994-8 2005 In addition, digoxin and taurocholate, substrates for organic anion transporting polypeptide subtype 2 (Oatp2), significantly inhibited [(3)H]PGE(1) uptake. Taurocholic Acid 25-37 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 104-109 10908301-3 2000 As with Oatp1, uptake of 10 microM [(3)H]taurocholate in Oatp2-expressing Xenopus laevis oocytes was trans-stimulated by intracellular 0.2 mM unlabeled taurocholate, indicating bidirectional transport. Taurocholic Acid 41-53 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 57-62 11792694-9 2002 These results suggest that rOatp2 has at least two substrate recognition sites, one for TCA and digoxin and the other for E(2)17betaG. Taurocholic Acid 88-91 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 27-33 10869292-5 2000 In contrast, sodium-independent taurocholate uptake mediated by the organic anion transporting polypeptides, Oatp1 and Oatp2, was already substantially inhibited by 10 micromol/L rifamycin SV. Taurocholic Acid 32-44 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 119-124 10869292-6 2000 Rifampicin potently inhibited Oatp2-mediated taurocholate uptake, but did not interfere with Oatp1-mediated taurocholate uptake. Taurocholic Acid 45-57 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 30-35 9294213-5 1997 In functional expression studies in Xenopus laevis oocytes, oatp2 mediated uptake of the bile acids taurocholate (Km approximately 35 microM) and cholate (Km approximately 46 microM), the estrogen conjugates 17beta-estradiol-glucuronide (Km approximately 3 microM) and estrone-3-sulfate (Km approximately 11 microM), and the cardiac gylcosides ouabain (Km approximately 470 microM) and digoxin (Km approximately 0.24 microM). Taurocholic Acid 100-112 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 60-65 9712861-1 1998 Two complementary DNAs for the organic anion transporter subtypes oatp2 and oatp3, which transport thyroid hormones as well as taurocholate, were isolated from a rat retina cDNA library. Taurocholic Acid 127-139 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 66-71 9712861-10 1998 Oocytes injected with oatp2 and oatp3 cRNAs showed taurocholate uptake in a saturable manner. Taurocholic Acid 51-63 solute carrier organic anion transporter family, member 1a4 Rattus norvegicus 22-27