PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32294204-5	2020	The apparent half-maximal inhibitory concentrations for OSTalpha/beta-mediated bile acid (5microM) transport inhibition by fidaxomicin, troglitazone sulfate and ethinyl estradiol were: 210, 334 and 1050microM, respectively, for taurochenodeoxycholate; 97.6, 333 and 337microM, respectively, for glycochenodeoxycholate; 140, 265 and 527microM, respectively, for taurocholate; 59.8, 102 and 117microM, respectively, for glycocholate.	Taurocholic Acid	361-373	solute carrier family 51 subunit alpha	Homo sapiens	56-69	
32294204-4	2020	Kinetic studies with OSTalpha/beta-overexpressing cells revealed that OSTalpha/beta preferentially transported bile acids in the following order: taurochenodeoxycholate>glycochenodeoxycholate>taurocholate>glycocholate.	Taurocholic Acid	192-204	solute carrier family 51 subunit alpha	Homo sapiens	70-83	
29420067-8	2018	Studies in the novel cell-based system showed rapid and linear OSTalpha/beta-mediated transport for all tested compounds: dehydroepiandrosterone sulfate, digoxin, estrone sulfate, and taurocholate.	Taurocholic Acid	184-196	solute carrier family 51 subunit alpha	Homo sapiens	63-71	
29420067-10	2018	Additionally, some drugs (e.g., digoxin) consistently stimulated taurocholate uptake in OSTalpha/beta-overexpressing cells.	Taurocholic Acid	65-77	solute carrier family 51 subunit alpha	Homo sapiens	88-101	
17332473-4	2007	The results demonstrated that coexpression of hOST-alpha and -beta in transfected cells resulted in a three- to fivefold increase of the initial rate of taurocholate influx or efflux compared with cells expressing each protein individually and nontransfected cells.	Taurocholic Acid	153-165	solute carrier family 51 subunit alpha	Homo sapiens	46-66	
29487110-10	2018	Increased basolateral efflux of TCA was consistent with increased OSTalpha/beta protein expression in OCA- and CDCA-treated SCHH.	Taurocholic Acid	32-35	solute carrier family 51 subunit alpha	Homo sapiens	66-79	
17332473-7	2007	Truncation of the amino-terminal 50 amino acid extracellular residues of hOST-alpha abolished its interaction with hOST-beta and led to an intracellular accumulation of the two proteins and to only background levels of taurocholate transport.	Taurocholic Acid	219-231	solute carrier family 51 subunit alpha	Homo sapiens	73-83	
12719432-7	2003	Human and mouse OSTalpha-OSTbeta also were able to mediate transport of taurocholate, digoxin, and prostaglandin E2 but not of estradiol 17beta-d-glucuronide or p-aminohippurate.	Taurocholic Acid	72-84	solute carrier family 51 subunit alpha	Homo sapiens	16-24	
34599072-7	2021	Out of the ten OSTalpha/beta mutants investigated, four (S228K, T229S, Q269E, Q269K) exhibited decreased (3H)-taurocholate (TCA) uptake (ratio of geometric means relative to OSTalpha/beta WT of 0.76, 0.75, 0.79, 0.13, respectively).	Taurocholic Acid	110-122	solute carrier family 51 subunit alpha	Homo sapiens	15-28	
34599072-7	2021	Out of the ten OSTalpha/beta mutants investigated, four (S228K, T229S, Q269E, Q269K) exhibited decreased (3H)-taurocholate (TCA) uptake (ratio of geometric means relative to OSTalpha/beta WT of 0.76, 0.75, 0.79, 0.13, respectively).	Taurocholic Acid	124-127	solute carrier family 51 subunit alpha	Homo sapiens	15-28	
34599072-8	2021	Three OSTalpha/beta mutants (S228K, Q269K, E305A) had reduced (3H)-TCA efflux % (ratio of geometric means relative to OSTalpha/beta WT of 0.86, 0.65, 0.79, respectively).	Taurocholic Acid	67-70	solute carrier family 51 subunit alpha	Homo sapiens	6-19