PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24317697-6	2014	The crystal structure of an ASBT homologue from Neisseria meningitidis (ASBT(NM)) in detergent was reported recently, showing the protein in an inward-open conformation bound to two Na(+) and a taurocholic acid.	Taurocholic Acid	194-210	solute carrier family 10 member 2	Homo sapiens	28-32	
24317697-6	2014	The crystal structure of an ASBT homologue from Neisseria meningitidis (ASBT(NM)) in detergent was reported recently, showing the protein in an inward-open conformation bound to two Na(+) and a taurocholic acid.	Taurocholic Acid	194-210	solute carrier family 10 member 2	Homo sapiens	72-76	
21649730-9	2011	A novel variant, 790A>G, was also shown to exhibit near complete loss of taurocholate transport, similar to the previously identified ASBT missense mutations.	Taurocholic Acid	76-88	solute carrier family 10 member 2	Homo sapiens	137-141	
17038509-2	2007	Taurocholate flux was measured across human apical sodium-dependent bile acid transporter (hASBT)-Madin-Darby canine kidney monolayers on different occasions and kinetic parameters estimated with and without considering ABL.	Taurocholic Acid	0-12	solute carrier family 10 member 2	Homo sapiens	91-96	
34346218-3	2021	ASBT is responsible for most of the taurocholic acid (TC) uptake in Caco-2 cells.	Taurocholic Acid	36-52	solute carrier family 10 member 2	Homo sapiens	0-4	
16078136-6	2005	Western blot confirmed the expression of the recombinant hASBT; functionality was characterized using taurocholic acid.	Taurocholic Acid	102-118	solute carrier family 10 member 2	Homo sapiens	57-62	
16078136-7	2005	RESULTS: In the selected clone, hASBT-mediated taurocholate permeability across hASBT-MDCK monolayers was almost 25-fold higher with sodium, than without sodium where hASBT is not functional.	Taurocholic Acid	47-59	solute carrier family 10 member 2	Homo sapiens	32-37	
16078136-7	2005	RESULTS: In the selected clone, hASBT-mediated taurocholate permeability across hASBT-MDCK monolayers was almost 25-fold higher with sodium, than without sodium where hASBT is not functional.	Taurocholic Acid	47-59	solute carrier family 10 member 2	Homo sapiens	80-85	
16078136-7	2005	RESULTS: In the selected clone, hASBT-mediated taurocholate permeability across hASBT-MDCK monolayers was almost 25-fold higher with sodium, than without sodium where hASBT is not functional.	Taurocholic Acid	47-59	solute carrier family 10 member 2	Homo sapiens	80-85	
16078136-8	2005	In the presence of sodium, taurocholate and mannitol permeabilities were 23.0x10(-6) cm/sec and 2.60x10(-6) cm/s, respectively, indicating high hASBT functionality and monolayer integrity.	Taurocholic Acid	27-39	solute carrier family 10 member 2	Homo sapiens	144-149	
16078136-10	2005	Taurocholate uptake and inhibition kinetic parameters from hASBT-MDCK were similar to those obtained from hASBT-COS7 model, confirming hASBT functionality in hASBT-MDCK.	Taurocholic Acid	0-12	solute carrier family 10 member 2	Homo sapiens	59-64	
15832499-3	2004	The affinity of the prodrug for hASBT was determined through inhibition of taurocholate uptake by COS-7 cells transfected with hASBT (hASBT-COS).	Taurocholic Acid	75-87	solute carrier family 10 member 2	Homo sapiens	32-37	
11230727-3	2001	Expression of the apical sodium-dependent bile acid transporter (ASBT) and of the organic anion transporting polypeptide (OATP-A) was detected and associated with sodium-dependent and sodium-independent [(3)H]taurocholate uptake in BEC.	Taurocholic Acid	209-221	solute carrier family 10 member 2	Homo sapiens	18-63	
11230727-3	2001	Expression of the apical sodium-dependent bile acid transporter (ASBT) and of the organic anion transporting polypeptide (OATP-A) was detected and associated with sodium-dependent and sodium-independent [(3)H]taurocholate uptake in BEC.	Taurocholic Acid	209-221	solute carrier family 10 member 2	Homo sapiens	65-69	
34346218-3	2021	ASBT is responsible for most of the taurocholic acid (TC) uptake in Caco-2 cells.	Taurocholic Acid	54-56	solute carrier family 10 member 2	Homo sapiens	0-4	
34346218-5	2021	The results from the TC uptake assay using N-acetylcysteine suggested that the inhibitory effect of TF2A and TF2B was attributed to the oxidization of their benzotropolone rings and their covalent bonding with ASBT"s cysteine.	Taurocholic Acid	21-23	solute carrier family 10 member 2	Homo sapiens	210-214	
34346218-6	2021	TC uptake was reduced in the COS-7 cells expressing recombinant ASBT whose cysteine residues were mutated to alanine.	Taurocholic Acid	0-2	solute carrier family 10 member 2	Homo sapiens	64-68