PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16940989-1 2006 BACKGROUND AND PURPOSE: The types of hepatic microsomal cytochrome P450 (CYP) isozymes responsible for the metabolism of metformin in humans and rats have not been published to date. Metformin 121-130 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 56-71 16940989-1 2006 BACKGROUND AND PURPOSE: The types of hepatic microsomal cytochrome P450 (CYP) isozymes responsible for the metabolism of metformin in humans and rats have not been published to date. Metformin 121-130 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 73-76 30066055-4 2018 Recently, the diabetes drug metformin was found to inhibit CYP AA epoxygenase activity, allowing the design of more potent biguanides to target tumor growth. Metformin 28-37 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 59-62