PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34858397-8 2021 Finally, pre-treatment of monocytes with metformin strongly suppressed spike protein-mediated cytokine production and metabolic reprogramming. Metformin 41-50 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 71-76 34858397-10 2021 In summary, the SARS-CoV-2 spike protein induces a pro-inflammatory immunometabolic response in monocytes that can be suppressed by metformin, and metformin likewise suppresses inflammatory responses to live SARS-CoV-2. Metformin 132-141 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 27-32