PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25993324-5 2015 DMTU fully and reversibly inhibited rat UT-A1 and UT-B by a noncompetitive mechanism with IC50 of 2-3 mM. 1,3-dimethylthiourea 0-4 solute carrier family 14 member 1 (Kidd blood group) Rattus norvegicus 50-54 9545259-7 1998 UT3-mediated water and urea transport were weakly temperature-dependent (activation energy <4 kcal/mol), inhibited > 75% by the urea transport inhibitor 1,3-dimethylthiourea, but not inhibited by the water transport inhibitor HgCl2. 1,3-dimethylthiourea 159-179 solute carrier family 14 member 1 (Kidd blood group) Rattus norvegicus 0-3 25613743-2 2015 The urea analog dimethylthiourea (DMTU) was recently found to inhibit the UT isoforms UT-A1 (expressed in kidney tubule epithelium) and UT-B (expressed in kidney vasa recta endothelium) with IC50 of 2-3 mM, and was shown to have diuretic action when administered to rats. 1,3-dimethylthiourea 16-32 solute carrier family 14 member 1 (Kidd blood group) Rattus norvegicus 136-140 25613743-2 2015 The urea analog dimethylthiourea (DMTU) was recently found to inhibit the UT isoforms UT-A1 (expressed in kidney tubule epithelium) and UT-B (expressed in kidney vasa recta endothelium) with IC50 of 2-3 mM, and was shown to have diuretic action when administered to rats. 1,3-dimethylthiourea 34-38 solute carrier family 14 member 1 (Kidd blood group) Rattus norvegicus 136-140