PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23107872-9	2013	Ca(2+) ionophore ionomycin (1 muM) and oxidative stress (30-minute exposure to 0.3 mM of tert-butylhydroperoxide) increased annexin-V-binding, effects again blunted by 30 muM of probucol.	tert-Butylhydroperoxide	89-112	latexin	Homo sapiens	30-33	
26052623-6	2016	The protective effects of isolated compounds (10 and 20 muM) against oxidative stress induced by tert-butyl hydroperoxide (t-BHP) in HepG2 cells were investigated through the measurement of aspartate aminotransferase (AST), alanine transaminase (ALT), and superoxide dismutase (SOD) levels.	tert-Butylhydroperoxide	97-121	latexin	Homo sapiens	56-59	
26052623-6	2016	The protective effects of isolated compounds (10 and 20 muM) against oxidative stress induced by tert-butyl hydroperoxide (t-BHP) in HepG2 cells were investigated through the measurement of aspartate aminotransferase (AST), alanine transaminase (ALT), and superoxide dismutase (SOD) levels.	tert-Butylhydroperoxide	123-128	latexin	Homo sapiens	56-59	
26052623-8	2016	Oxidant-induced damage by 200 muM t-BHP in HepG2 cells was inhibited by compounds 1, 4, and 5 (10 and 20 muM), or quercetin (10 muM; positive control).	tert-Butylhydroperoxide	34-39	latexin	Homo sapiens	30-33	
26052623-8	2016	Oxidant-induced damage by 200 muM t-BHP in HepG2 cells was inhibited by compounds 1, 4, and 5 (10 and 20 muM), or quercetin (10 muM; positive control).	tert-Butylhydroperoxide	34-39	latexin	Homo sapiens	105-108	
26052623-8	2016	Oxidant-induced damage by 200 muM t-BHP in HepG2 cells was inhibited by compounds 1, 4, and 5 (10 and 20 muM), or quercetin (10 muM; positive control).	tert-Butylhydroperoxide	34-39	latexin	Homo sapiens	105-108	
24582277-6	2014	Among the tested compounds, 6"-O-caffeoylacteoside exhibited the most potent cytoprotective activity with an IC50 value of 0.8+-0.1 muM against t-BHP-induced toxicity.	tert-Butylhydroperoxide	144-149	latexin	Homo sapiens	132-135	
29630935-7	2018	The most sensitive and reliable combination for this ROS assay was 10 muM DCFDA with 25 muM TBHP; since higher concentrations of DCFDA compromised cell viability.	tert-Butylhydroperoxide	92-96	latexin	Homo sapiens	70-73	
29630935-7	2018	The most sensitive and reliable combination for this ROS assay was 10 muM DCFDA with 25 muM TBHP; since higher concentrations of DCFDA compromised cell viability.	tert-Butylhydroperoxide	92-96	latexin	Homo sapiens	88-91	
24486304-4	2014	KEY FINDINGS: When tBHP was used to induce lipid peroxidation, lycopene was the most efficient carotenoid (IC50=2.2 +- 0.4 muM), while lutein was the most efficient (IC50=2.5 +- 0.7 muM) when peroxyl radicals (ROO) were generated by AAPH.	tert-Butylhydroperoxide	19-23	latexin	Homo sapiens	123-126	
24486304-4	2014	KEY FINDINGS: When tBHP was used to induce lipid peroxidation, lycopene was the most efficient carotenoid (IC50=2.2 +- 0.4 muM), while lutein was the most efficient (IC50=2.5 +- 0.7 muM) when peroxyl radicals (ROO) were generated by AAPH.	tert-Butylhydroperoxide	19-23	latexin	Homo sapiens	182-185	
22610911-3	2013	Caco-2 cells pretreated with ferulate (5 or 15 muM) were exposed to t-BHP (100 muM), and ferulate suppressed the t-BHP-mediated increases in reactive species and epithelial permeability in Caco-2 cells.	tert-Butylhydroperoxide	68-73	latexin	Homo sapiens	79-82	
22610911-3	2013	Caco-2 cells pretreated with ferulate (5 or 15 muM) were exposed to t-BHP (100 muM), and ferulate suppressed the t-BHP-mediated increases in reactive species and epithelial permeability in Caco-2 cells.	tert-Butylhydroperoxide	113-118	latexin	Homo sapiens	47-50	
22610911-3	2013	Caco-2 cells pretreated with ferulate (5 or 15 muM) were exposed to t-BHP (100 muM), and ferulate suppressed the t-BHP-mediated increases in reactive species and epithelial permeability in Caco-2 cells.	tert-Butylhydroperoxide	113-118	latexin	Homo sapiens	79-82	
23107872-9	2013	Ca(2+) ionophore ionomycin (1 muM) and oxidative stress (30-minute exposure to 0.3 mM of tert-butylhydroperoxide) increased annexin-V-binding, effects again blunted by 30 muM of probucol.	tert-Butylhydroperoxide	89-112	latexin	Homo sapiens	171-174	
22956110-5	2012	Oxidative stress was induced by exposure of the cells to tert-butyl hydroperoxide (TBH) for 1 h. TBH (3,000 muM) induced an increase in biomarkers of oxidative stress, while maintaining cell viability and proliferation.	tert-Butylhydroperoxide	57-81	latexin	Homo sapiens	108-111	
22956110-5	2012	Oxidative stress was induced by exposure of the cells to tert-butyl hydroperoxide (TBH) for 1 h. TBH (3,000 muM) induced an increase in biomarkers of oxidative stress, while maintaining cell viability and proliferation.	tert-Butylhydroperoxide	83-86	latexin	Homo sapiens	108-111	
22956110-5	2012	Oxidative stress was induced by exposure of the cells to tert-butyl hydroperoxide (TBH) for 1 h. TBH (3,000 muM) induced an increase in biomarkers of oxidative stress, while maintaining cell viability and proliferation.	tert-Butylhydroperoxide	97-100	latexin	Homo sapiens	108-111	
22956110-6	2012	In relation to the apical uptake of (3)H-FA, TBH (3,000 muM) reduced the cellular accumulation of (3)H-FA (10 nM), although the characteristics (kinetics, pH dependence, and inhibitory profile) of (3)H-FA uptake were not changed.	tert-Butylhydroperoxide	45-48	latexin	Homo sapiens	56-59	
20510595-6	2011	Under 400 muM t-BHP treatment, QZG cell displayed significant loss of viability and dramatic morphological changes characterized by changing in shape from triangle to spherical, disappearance of cell cilia, swollen mitochondrial and typical apoptotic alteration such as condensation of chromatin, and appearance of crescent under light microscopy and electronic microscopy, respectively.	tert-Butylhydroperoxide	14-19	latexin	Homo sapiens	10-13	
20510595-9	2011	25 muM rosiglitazone treatment inhibited the t-BHP-induced cell toxicity significantly by restoring the cell viability, reducing cell population undergone apoptosis to normal level (3.5%) and ameliorating t-BHP-induced pathological changes.	tert-Butylhydroperoxide	45-50	latexin	Homo sapiens	3-6	
20510595-9	2011	25 muM rosiglitazone treatment inhibited the t-BHP-induced cell toxicity significantly by restoring the cell viability, reducing cell population undergone apoptosis to normal level (3.5%) and ameliorating t-BHP-induced pathological changes.	tert-Butylhydroperoxide	205-210	latexin	Homo sapiens	3-6	
20510595-10	2011	Real-time RT-PCR results showed that 400 muM t-BHP caused dramatic down-regulation of PPARgamma expression in QZG cells, whereas combining treatment with 25 muM rosiglitazone resistant to PPARgamma expression to normal level partially.	tert-Butylhydroperoxide	45-50	latexin	Homo sapiens	41-44	
21707031-8	2011	Oxidative stress (30 min 0.3 mM tert-butylhydroperoxide) again significantly increased Fluo-3 fluorescence and triggered annexin binding, effects again in part significantly blunted by phlorhizin (Fluo-3 fluorescence >= 50 muM, annexin-binding >= 10 muM).	tert-Butylhydroperoxide	32-55	latexin	Homo sapiens	226-229	
21707031-8	2011	Oxidative stress (30 min 0.3 mM tert-butylhydroperoxide) again significantly increased Fluo-3 fluorescence and triggered annexin binding, effects again in part significantly blunted by phlorhizin (Fluo-3 fluorescence >= 50 muM, annexin-binding >= 10 muM).	tert-Butylhydroperoxide	32-55	latexin	Homo sapiens	256-259