PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26205049-3 2015 Furthermore, licorice extract inhibited the expression levels of pro-inflammatory cytokines (TNF-alpha, IL-1beta and IL-6) in the livers of t-BHP-treated mice models. tert-Butylhydroperoxide 140-145 tumor necrosis factor Mus musculus 93-102 29371164-5 2018 Thus, Avns reduced IKKbeta kinase activity in response to tert-butyl hydroperoxide (tBHP) stimulation and attenuated tBHP-induced TNFalpha and IL-1beta mRNA expression. tert-Butylhydroperoxide 117-121 tumor necrosis factor Mus musculus 130-138 31772142-6 2019 Additionally, Ast alleviated TNF-alpha-induced ECM degradation and chondrocyte apoptosis by inhibiting the NF-kappaB signaling, suppressed TBHP-induced oxidative stress, and subsequently reduced chondrocyte apoptosis. tert-Butylhydroperoxide 139-143 tumor necrosis factor Mus musculus 29-38 17129690-3 2007 In this study, we examined the effect of the oxidant tert-butylhydroperoxide (tBHP) on mouse J774 macrophages and its ability to cause the release of the pro-inflammatory cytokine tumour necrosis factor alpha (TNF-alpha). tert-Butylhydroperoxide 53-76 tumor necrosis factor Mus musculus 210-219 22508061-9 2012 The effect of rapamycin on TNF-alpha release was also mimicked by the antioxidant ROS scavenger Tempol (30 muM) and partially reversed by additional application of tert-butylhydroperoxide (10 muM). tert-Butylhydroperoxide 164-187 tumor necrosis factor Mus musculus 27-36 17369293-2 2007 We have now studied the ability of oxidative stress induced by a synthetic oxidant tert-butyl hydroperoxide (tBHP) to induce TNF-alpha production via calcium signaling in the mouse macrophage cell line (J774). tert-Butylhydroperoxide 83-107 tumor necrosis factor Mus musculus 125-134 17369293-2 2007 We have now studied the ability of oxidative stress induced by a synthetic oxidant tert-butyl hydroperoxide (tBHP) to induce TNF-alpha production via calcium signaling in the mouse macrophage cell line (J774). tert-Butylhydroperoxide 109-113 tumor necrosis factor Mus musculus 125-134 17369293-3 2007 The oxidant tBHP significantly increased intracellular calcium and the release of TNF-alpha in J774 cells, an effect that was reduced to control levels by inhibition of calcium signaling with verapamil, BAPTA-AM, and W-7. tert-Butylhydroperoxide 12-16 tumor necrosis factor Mus musculus 82-91 17129690-3 2007 In this study, we examined the effect of the oxidant tert-butylhydroperoxide (tBHP) on mouse J774 macrophages and its ability to cause the release of the pro-inflammatory cytokine tumour necrosis factor alpha (TNF-alpha). tert-Butylhydroperoxide 78-82 tumor necrosis factor Mus musculus 210-219 17129690-8 2007 The production of TNF-alpha protein by J774 macrophages was mediated by a pathway involving calcium as addition of calcium antagonists inhibited the tBHP stimulated increase in the cytokine. tert-Butylhydroperoxide 149-153 tumor necrosis factor Mus musculus 18-27 17129690-9 2007 Inhibitors of both PDE1 and PDE4 completely prevented the tBHP stimulated TNF-alpha release suggesting that the cAMP pathway may be important in the oxidant induced signalling pathway leading to gene expression of pro-inflammatory cytokines. tert-Butylhydroperoxide 58-62 tumor necrosis factor Mus musculus 74-83 34409026-6 2021 TNFalpha treatment potentiated the brain endothelial erythrophagocytosis of tBHP-RBCs in vitro. tert-Butylhydroperoxide 76-80 tumor necrosis factor Mus musculus 0-8