PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21391895-4	2011	TBHP also activated phospho-ERK1/2, phospho-p38 and NF-kappaB, altered the Bcl-2/Bad ratio, reduced mitochondrial membrane potential, released cytochrome C and activated caspase 3, suggesting that TBHP induced oxidative stress responsive cell death via apoptotic pathway.	tert-Butylhydroperoxide	0-4	caspase 3	Mus musculus	170-179	
22518128-10	2012	Exendin-4 was found to inhibit t-BHP-induced apoptosis in pancreatic beta-cells by downregulating caspase-3 activity.	tert-Butylhydroperoxide	31-36	caspase 3	Mus musculus	98-107	
19647727-4	2009	Pretreatment of Hepa1c1c7 cells with CDCQ significantly reduced t-BHP-induced generation of ROS, caspase-3 activation, and subsequent cell death.	tert-Butylhydroperoxide	64-69	caspase 3	Mus musculus	97-106	
18979186-13	2009	Hence, the present study indicates the involvement and activation of various apoptotic factors, particularly Caspase 3 and 9 along with p53, in response to exposure of testicular cells to DEM and TBHP.	tert-Butylhydroperoxide	196-200	caspase 3	Mus musculus	109-118	
19664004-3	2009	In particular, melatonin (10(-4)-10(-6) m) fully prevented myotube death induced by tert-butylhydroperoxide (t-BHP; 10 microm-24 hr) as assessed by acid phosphatase, caspase-3 activities and cellular morphological changes.	tert-Butylhydroperoxide	109-114	caspase 3	Mus musculus	166-175