PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30538149-5 2019 During this time period, HO-1 induction fully prevented the pro-oxidant tert-butylhydroperoxide (tBuOOH)-induced drop in bile flow, and in the biliary excretion of bile salts and glutathione, the two main driving forces of bile flow; this was associated with preservation of the membrane localization of their respective canalicular transporters, bile salt export pump (Bsep) and multidrug resistance-associated protein 2 (Mrp2), which are otherwise endocytosed by OS. tert-Butylhydroperoxide 72-95 ATP binding cassette subfamily B member 11 Rattus norvegicus 347-368 30538149-5 2019 During this time period, HO-1 induction fully prevented the pro-oxidant tert-butylhydroperoxide (tBuOOH)-induced drop in bile flow, and in the biliary excretion of bile salts and glutathione, the two main driving forces of bile flow; this was associated with preservation of the membrane localization of their respective canalicular transporters, bile salt export pump (Bsep) and multidrug resistance-associated protein 2 (Mrp2), which are otherwise endocytosed by OS. tert-Butylhydroperoxide 72-95 ATP binding cassette subfamily B member 11 Rattus norvegicus 370-374 30538149-5 2019 During this time period, HO-1 induction fully prevented the pro-oxidant tert-butylhydroperoxide (tBuOOH)-induced drop in bile flow, and in the biliary excretion of bile salts and glutathione, the two main driving forces of bile flow; this was associated with preservation of the membrane localization of their respective canalicular transporters, bile salt export pump (Bsep) and multidrug resistance-associated protein 2 (Mrp2), which are otherwise endocytosed by OS. tert-Butylhydroperoxide 97-103 ATP binding cassette subfamily B member 11 Rattus norvegicus 347-368 30538149-5 2019 During this time period, HO-1 induction fully prevented the pro-oxidant tert-butylhydroperoxide (tBuOOH)-induced drop in bile flow, and in the biliary excretion of bile salts and glutathione, the two main driving forces of bile flow; this was associated with preservation of the membrane localization of their respective canalicular transporters, bile salt export pump (Bsep) and multidrug resistance-associated protein 2 (Mrp2), which are otherwise endocytosed by OS. tert-Butylhydroperoxide 97-103 ATP binding cassette subfamily B member 11 Rattus norvegicus 370-374 27913845-1 2017 In previous studies, we showed that the pro-oxidant model agent tert-butyl hydroperoxide (tBuOOH) induces alterations in hepatocanalicular secretory function by activating Ca2+-dependent protein kinase C isoforms (cPKC), via F-actin disorganization followed by endocytic internalization of canalicular transporters relevant to bile formation (Mrp2, Bsep). tert-Butylhydroperoxide 64-88 ATP binding cassette subfamily B member 11 Rattus norvegicus 349-353 16452108-4 2006 tBOOH-induced bile salt secretory failure was accompanied by internalization of the canalicular bile salt export pump (Bsep), and disarrangement of cytoskeletal F-actin. tert-Butylhydroperoxide 0-5 ATP binding cassette subfamily B member 11 Rattus norvegicus 96-117 16452108-4 2006 tBOOH-induced bile salt secretory failure was accompanied by internalization of the canalicular bile salt export pump (Bsep), and disarrangement of cytoskeletal F-actin. tert-Butylhydroperoxide 0-5 ATP binding cassette subfamily B member 11 Rattus norvegicus 119-123