PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33321464-7	2021	Nrf2a was also stabilized in beta-cells: 10-min exposures to 77.6 muM tert-butylhydroperoxide significantly increased Nrf2a protein compared to control islet cells that largely lack stabilized Nrf2a; 10-min exposures to higher (776 muM) tert-butylhydroperoxide concentration stabilized Nrf2a throughout the pancreas.	tert-Butylhydroperoxide	70-93	nfe2 like bZIP transcription factor 2a	Danio rerio	0-5	
24298298-7	2013	nrf genes were induced by the oxidant tert-butylhydroperoxide, and some of this response was regulated through family members Nrf2a and Nrf2b.	tert-Butylhydroperoxide	38-61	nfe2 like bZIP transcription factor 2a	Danio rerio	126-131	
22174413-7	2012	Embryos in which Nrf2a expression had been knocked down with morpholino oligonucleotides were more sensitive to tert-butylhydroperoxide but not tert-butylhydroquinone, whereas knockdown of Nrf2b did not affect sensitivity of embryos to either chemical.	tert-Butylhydroperoxide	112-135	nfe2 like bZIP transcription factor 2a	Danio rerio	17-22	
19233942-9	2009	Knockdown of NRF2 increased mortality following tBOOH challenge, prevented significant upregulation of antioxidant genes following both tBOOH and BNF + ANF exposures, and exacerbated BNF + ANF-related deformities.	tert-Butylhydroperoxide	48-53	nfe2 like bZIP transcription factor 2a	Danio rerio	13-17	
19233942-9	2009	Knockdown of NRF2 increased mortality following tBOOH challenge, prevented significant upregulation of antioxidant genes following both tBOOH and BNF + ANF exposures, and exacerbated BNF + ANF-related deformities.	tert-Butylhydroperoxide	136-141	nfe2 like bZIP transcription factor 2a	Danio rerio	13-17	
28212397-5	2017	Both methods showed that exposure to tBHP and Cd induced expression of prdx1, gstp1, and hmox1a (2- to 12-fold increase via QGP), indicative of an activated Nrf2 response in larval zebrafish.	tert-Butylhydroperoxide	37-41	nfe2 like bZIP transcription factor 2a	Danio rerio	157-161	
33321464-7	2021	Nrf2a was also stabilized in beta-cells: 10-min exposures to 77.6 muM tert-butylhydroperoxide significantly increased Nrf2a protein compared to control islet cells that largely lack stabilized Nrf2a; 10-min exposures to higher (776 muM) tert-butylhydroperoxide concentration stabilized Nrf2a throughout the pancreas.	tert-Butylhydroperoxide	70-93	nfe2 like bZIP transcription factor 2a	Danio rerio	118-123	
33321464-7	2021	Nrf2a was also stabilized in beta-cells: 10-min exposures to 77.6 muM tert-butylhydroperoxide significantly increased Nrf2a protein compared to control islet cells that largely lack stabilized Nrf2a; 10-min exposures to higher (776 muM) tert-butylhydroperoxide concentration stabilized Nrf2a throughout the pancreas.	tert-Butylhydroperoxide	70-93	nfe2 like bZIP transcription factor 2a	Danio rerio	118-123	
33321464-7	2021	Nrf2a was also stabilized in beta-cells: 10-min exposures to 77.6 muM tert-butylhydroperoxide significantly increased Nrf2a protein compared to control islet cells that largely lack stabilized Nrf2a; 10-min exposures to higher (776 muM) tert-butylhydroperoxide concentration stabilized Nrf2a throughout the pancreas.	tert-Butylhydroperoxide	70-93	nfe2 like bZIP transcription factor 2a	Danio rerio	118-123	
33321464-7	2021	Nrf2a was also stabilized in beta-cells: 10-min exposures to 77.6 muM tert-butylhydroperoxide significantly increased Nrf2a protein compared to control islet cells that largely lack stabilized Nrf2a; 10-min exposures to higher (776 muM) tert-butylhydroperoxide concentration stabilized Nrf2a throughout the pancreas.	tert-Butylhydroperoxide	237-260	nfe2 like bZIP transcription factor 2a	Danio rerio	0-5	
33321464-9	2021	The 10-min high (776 muM) tert-butylhydroperoxide exposure (induced Nrf2a globally) decreased global protein glutathionylation at 96 hpf.	tert-Butylhydroperoxide	26-49	nfe2 like bZIP transcription factor 2a	Danio rerio	68-73	
33321464-10	2021	Mutant fish expressing inactive Nrf2a were protected against tert-butylhydroperoxide-induced abnormal islet morphology.	tert-Butylhydroperoxide	61-84	nfe2 like bZIP transcription factor 2a	Danio rerio	32-37	
31858786-7	2020	Nrf2a LOF mutants showed increased sensitivity to the acute toxicity of cumene hydroperoxide (CHP) and tBHP throughout the first four days of development.	tert-Butylhydroperoxide	103-107	nfe2 like bZIP transcription factor 2a	Danio rerio	0-5