PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24741394-5 2014 Moreover, TBHP-induced oxidative stress resulted in a transient ERK1/2 activation and a sustained increase of JNK1/2 activation. tert-Butylhydroperoxide 10-14 mitogen-activated protein kinase 3 Homo sapiens 64-70 32331354-7 2020 The protective effect of crocetin is mediated via the preservation of energy production pathways and activation of ERK1/2 in the first minutes of TBHP exposure to potentiate survival pathways. tert-Butylhydroperoxide 146-150 mitogen-activated protein kinase 3 Homo sapiens 115-121 24857917-0 2014 The cytoprotective effect of sulfuretin against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2/ARE and JNK/ERK MAPK-mediated heme oxygenase-1 expression. tert-Butylhydroperoxide 48-72 mitogen-activated protein kinase 3 Homo sapiens 125-129 18666426-7 2008 It was found that genistein, at 1 microM, diminished t-BHP-induced down-regulation of the IGF-I receptor, Shc, Sos and phosphorylated ERK1/ERK2 expression in fibroblasts. tert-Butylhydroperoxide 53-58 mitogen-activated protein kinase 3 Homo sapiens 134-138 18666426-9 2008 These results suggest that the mechanism of the protective effect of genistein on collagen biosynthesis in t-BHP-treated fibroblasts may be due to prevention of disturbances in the IGF-I receptor-mediated, ERK1/ERK2-associated signaling pathway evoked by the oxidant. tert-Butylhydroperoxide 107-112 mitogen-activated protein kinase 3 Homo sapiens 206-210 16705147-7 2006 In contrast, activation of ERK1/2 by expression of constitutively active MEK1 suppressed basal, uncoupled, and state 3 respirations in noninjured RPTC to the levels observed in TBHP-injured RPTC. tert-Butylhydroperoxide 177-181 mitogen-activated protein kinase 3 Homo sapiens 27-33 16705147-3 2006 Sublethal injury produced by tert-butylhydroperoxide (TBHP) resulted in three- to fivefold increase in phosphorylation of ERK1/2 and p38 but not JNK. tert-Butylhydroperoxide 29-52 mitogen-activated protein kinase 3 Homo sapiens 122-128 16705147-3 2006 Sublethal injury produced by tert-butylhydroperoxide (TBHP) resulted in three- to fivefold increase in phosphorylation of ERK1/2 and p38 but not JNK. tert-Butylhydroperoxide 54-58 mitogen-activated protein kinase 3 Homo sapiens 122-128 16028365-6 2005 Pretreatment with the p38 MAP kinase inhibitor, SB203580 and the ERK1/2 inhibitor, PD98059, prevented t-BHP-induced increases in p65 translocation, NF-kappaB luciferase activity, and phospho-IKKalpha/beta. tert-Butylhydroperoxide 102-107 mitogen-activated protein kinase 3 Homo sapiens 65-71