PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28414098-3 2017 In this study, a RIP1/RIP3 complex was formed in 2-methoxy-6-acetyl-7-methyljuglone (MAM)-treated HCT116 and HT29 colon cancer cells. methylazoxymethanol 85-88 receptor interacting serine/threonine kinase 3 Homo sapiens 22-26 28414098-6 2017 This finding was confirmed by experiments showing that MAM-induced cell death was attenuated by the pharmacological or genetic blockage of necroptosis signaling, including RIP1 inhibitor necrostatin-1s (Nec-1s) and siRNA-mediated gene silencing of RIP1 and RIP3, but was unaffected by caspase inhibitor z-vad-fmk or necrosis inhibitor 2-(1H-Indol-3-yl)-3-pentylamino-maleimide (IM54). methylazoxymethanol 55-58 receptor interacting serine/threonine kinase 3 Homo sapiens 257-261