PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8820970-5 1996 The shift in sedimentation values of the separated AChE and BuChE species in sucrose gradients made with and without detergents revealed the occurrence of hydrophilic (H) and amphiphilic (A) variants of cholinesterases in the extracts. Sucrose 77-84 acetylcholinesterase Mus musculus 51-55 7512968-4 1994 About 22% of the cell-associated AChE was membrane-linked as dimers and tetramers, required Triton X-100 for extraction, and bound to Triton X-100 as assessed by sucrose gradients. Sucrose 162-169 acetylcholinesterase Mus musculus 33-37 8408164-7 1993 AChE activity was measured by differential extraction and velocity sedimentation on sucrose gradients. Sucrose 84-91 acetylcholinesterase Mus musculus 0-4 1760105-3 1991 AChE activity at 3 weeks postburn was measured by differential extraction and velocity sedimentation on sucrose gradients. Sucrose 104-111 acetylcholinesterase Mus musculus 0-4 19651088-4 1988 Among the several molecular forms of AChE, PIPLC specifically releases in a dose dependent manner one molecular form which migrates on linear sucrose gradients as a single peak of sedimentation coefficient 6.3 s. In other subcellular membrane fractions, including motor endplate enriched fraction, PIPLC fails to solubilize AChE. Sucrose 142-149 acetylcholinesterase Mus musculus 37-41 3694264-4 1987 In normal mouse biceps the distribution of AChE forms, as shown by sucrose-gradient analysis, change substantially after birth; the most dramatic alteration is an increase in G4 AChE from 15 to 45% of total AChE during the third postnatal week. Sucrose 67-74 acetylcholinesterase Mus musculus 43-47 3449398-1 1987 The pattern of acetylcholinesterase (AChE) molecular forms, obtained by sucrose gradient sedimentation, was studied at different in vitro developmental stages of myogenic cells isolated from adult mouse skeletal muscle. Sucrose 72-79 acetylcholinesterase Mus musculus 37-41 3748455-4 1986 Sucrose density sedimentation analysis of muscle homogenates revealed an increase, by 2-3 times, in the proportion of the asymmetric (16S) molecular form of AChE in active muscle of both genotypes. Sucrose 0-7 acetylcholinesterase Mus musculus 157-161 6237698-1 1984 Acetylcholinesterase (AChE) is composed of several distinct molecular forms, which are identified and partly resolved by velocity sedimentation analysis on sucrose gradients. Sucrose 156-163 acetylcholinesterase Mus musculus 0-20 6237698-1 1984 Acetylcholinesterase (AChE) is composed of several distinct molecular forms, which are identified and partly resolved by velocity sedimentation analysis on sucrose gradients. Sucrose 156-163 acetylcholinesterase Mus musculus 22-26 6237698-2 1984 We made the assumption that each AChE form sediments as a peak of activity with a gaussian shape in the continuous sucrose gradient. Sucrose 115-122 acetylcholinesterase Mus musculus 33-37 6656838-1 1983 Acetylcholinesterase (AChE) was extracted from normal and dystrophic C57BL/6J mouse hindlimb muscles and its molecular forms fractionated by sucrose density gradient ultracentrifugation. Sucrose 141-148 acetylcholinesterase Mus musculus 0-20 6656838-1 1983 Acetylcholinesterase (AChE) was extracted from normal and dystrophic C57BL/6J mouse hindlimb muscles and its molecular forms fractionated by sucrose density gradient ultracentrifugation. Sucrose 141-148 acetylcholinesterase Mus musculus 22-26 6617773-4 1983 Three forms of AChE, distinguished by their sedimentation on sucrose gradients, were synthesized: 4-6S, 10S, and 16S. Sucrose 61-68 acetylcholinesterase Mus musculus 15-19 6128176-9 1982 The acetylcholinesterase activities released by proteolytic enzymes were characterized by sucrose density gradient centrifugation. Sucrose 90-97 acetylcholinesterase Mus musculus 4-24 750918-4 1978 The patterns of AChE activity, as separated by sucrose density gradient centrifugation, were distinctly different in extracts of dystrophic and normal muscle. Sucrose 47-54 acetylcholinesterase Mus musculus 16-20 33322722-0 2020 Impact of Sucrose as Osmolyte on Molecular Dynamics of Mouse Acetylcholinesterase. Sucrose 10-17 acetylcholinesterase Mus musculus 61-81 33322722-1 2020 The enzyme model, mouse acetylcholinesterase, which exhibits its active site at the bottom of a narrow gorge, was investigated in the presence of different concentrations of sucrose to shed light on the protein and water dynamics in cholinesterases. Sucrose 174-181 acetylcholinesterase Mus musculus 24-44 29862455-7 2018 We demonstrate that high sucrose consumption and DSP4 treatment promote an early-stage AD-related phenotype after only 3-4 months, as evidenced by elevated fecal corticosterone, increased despair, spatial memory deficits, increased AChE activity, elevated NO production, decreased pGSK3beta and increased pTau. Sucrose 25-32 acetylcholinesterase Mus musculus 232-236