PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11435219-0 2001 Role of p38 MAP kinase in diperoxovanadate-induced phospholipase D activation in endothelial cells. diperoxovanadate 26-42 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 51-66 11435219-1 2001 We previously demonstrated that diperoxovanadate (DPV), a synthetic peroxovanadium compound and cell-permeable oxidant that acts as a protein tyrosine phosphatase inhibitor and insulinomimetic, increased phospholipase D (PLD) activation in endothelial cells (ECs). diperoxovanadate 32-48 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 204-219 11435219-1 2001 We previously demonstrated that diperoxovanadate (DPV), a synthetic peroxovanadium compound and cell-permeable oxidant that acts as a protein tyrosine phosphatase inhibitor and insulinomimetic, increased phospholipase D (PLD) activation in endothelial cells (ECs). diperoxovanadate 32-48 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 221-224 11435219-1 2001 We previously demonstrated that diperoxovanadate (DPV), a synthetic peroxovanadium compound and cell-permeable oxidant that acts as a protein tyrosine phosphatase inhibitor and insulinomimetic, increased phospholipase D (PLD) activation in endothelial cells (ECs). diperoxovanadate 50-53 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 204-219 11435219-1 2001 We previously demonstrated that diperoxovanadate (DPV), a synthetic peroxovanadium compound and cell-permeable oxidant that acts as a protein tyrosine phosphatase inhibitor and insulinomimetic, increased phospholipase D (PLD) activation in endothelial cells (ECs). diperoxovanadate 50-53 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 221-224 11435219-2 2001 In this report, the regulation of DPV-induced PLD activation by mitogen-activated protein kinases (MAPKs) was investigated. diperoxovanadate 34-37 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 46-49 11435219-4 2001 Treatment of ECs with p38 MAPK inhibitors SB-203580 and SB-202190 or transient transfection with a p38 dominant negative mutant mitigated the PLD activation by DPV but not by phorbol ester. diperoxovanadate 160-163 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 142-145 11228747-3 1999 Previously, we have shown that ROS (hydrogen peroxide, fatty acid hydroperoxide, diperoxovanadate, and 4-hydroxynonenal) enhance protein tyrosine phosphorylation and activate phospholipase D (PLD) in bovine pulmonary artery endothelial cells (BPAECs). diperoxovanadate 81-97 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 192-195