PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11061215-7	2000	3D-QSAR with CoMFA of isatin and pirlindole analogues of MAO A and B revealed differences in the models of MAO A and B.	pirlindole	33-43	monoamine oxidase A	Homo sapiens	57-62	
11061215-7	2000	3D-QSAR with CoMFA of isatin and pirlindole analogues of MAO A and B revealed differences in the models of MAO A and B.	pirlindole	33-43	monoamine oxidase A	Homo sapiens	57-68	
9703624-4	1998	The administration of MAO a inhibitor pyrazidol promoted the increase in brain serotonin content, normalized brain catecholamine contents and demonstrated positive effect on the animal state.	pirlindole	38-47	monoamine oxidase A	Homo sapiens	22-27	
9564636-0	1998	The influence of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase A and GABAA receptor binding.	pirlindole	36-46	monoamine oxidase A	Homo sapiens	93-112	
29221756-8	2018	A monoamine oxidase A inhibitor, pirlindole mesylate showed only weak displacement of [3H]d-deprenyl binding.	pirlindole	33-52	monoamine oxidase A	Homo sapiens	2-21	
21075154-10	2011	Deprenyl itself as well as the MAO-B antagonist rasagiline did effectively block the binding of the radioligand, whereas the MAO-A antagonist pirlindole did not affect it.	pirlindole	142-152	monoamine oxidase A	Homo sapiens	125-130	
15056494-3	2004	CD spectra of MAO A indicate that a small inhibitor such d-amphetamine perturbs the aromatic residues very little, but binding of the larger pirlindole (2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-j,k]carbazole hydrochloride) causes spectral changes consistent with the alteration of the environment of tyrosine and tryptophan residues in particular.	pirlindole	141-153	monoamine oxidase A	Homo sapiens	14-19	
10591049-1	1999	A series of pirlindole analogues were tested as inhibitors of monoamine oxidase A and B.	pirlindole	12-22	monoamine oxidase A	Homo sapiens	62-87	
9272198-0	1997	Double-blind randomized controlled study of the efficacy and tolerability of two reversible monoamine oxidase A inhibitors, pirlindole and moclobemide, in the treatment of depression.	pirlindole	124-134	monoamine oxidase A	Homo sapiens	92-111	
9272198-1	1997	The aim of this double-blind randomized study was to compare the efficacy and the tolerability of moclobemide (300-600 mg daily) and pirlindole (150-300 mg daily), two reversible inhibitors of MAO-A (RIMAs), in the treatment of depression.	pirlindole	133-143	monoamine oxidase A	Homo sapiens	193-198	
9020990-0	1996	A double-blind randomized placebo-controlled study of the efficacy and safety of pirlindole, a reversible monoamine oxidase A inhibitor, in the treatment of depression.	pirlindole	81-91	monoamine oxidase A	Homo sapiens	106-125	
9020990-1	1996	The efficacy and safety of pirlindole (300 mg/day), a new reversible inhibitor of monoamine oxidase A, have been evaluated in a multicentre placebo-controlled double-blind randomized trial in 103 in-patients suffering from unipolar major depression (DSM-III-R 296.2, 296.3) over a 42-day period after a run-in placebo period of 6 days.	pirlindole	27-37	monoamine oxidase A	Homo sapiens	82-101	
8953568-0	1996	Effects of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase-A and on GABAA receptors.	pirlindole	30-40	monoamine oxidase A	Homo sapiens	87-106	
6649522-0	1983	[Selective inhibition by pyrazidol of monoamine oxidase type A in different human and animal tissues].	pirlindole	25-34	monoamine oxidase A	Homo sapiens	38-62	
21877764-3	2011	Pirlindole is a selective and reversible inhibitor of monoamine oxidase (MAO) subtype A (MAO-A) that is approved in some European and non-European countries for the treatment of depression.	pirlindole	0-10	monoamine oxidase A	Homo sapiens	89-94	
12781338-0	2003	Monoamine oxidase A inhibitory potency and flavin perturbation are influenced by different aspects of pirlindole inhibitor structure.	pirlindole	102-112	monoamine oxidase A	Homo sapiens	0-19	
12781338-3	2003	The kinetic, spectral, and thermodynamic changes induced by four closely related pirlindole analogues have been determined to investigate their interaction with the FAD in the active site of MAO A.	pirlindole	81-91	monoamine oxidase A	Homo sapiens	191-196	
12679138-1	2003	We have previously shown that pirlindole and dehydropirlindole, two monoamine oxidase type-A inhibitors, protect cultured brain cells against iron-induced toxicity through a mechanism unrelated to monoamine oxidase type-A inhibition.	pirlindole	30-40	monoamine oxidase A	Homo sapiens	68-92