PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23300791-4	2012	Loss- and gain-of-function experiments in human bronchial epithelial and lung carcinoma cell lines revealed that Ascl1, MMP-7 and MGMT are able to protect cells from the tobacco-specific nitrosamine NNK-induced DNA damage and the alkylating agent cisplatin-induced apoptosis.	Nitrosamines	187-198	O-6-methylguanine-DNA methyltransferase	Homo sapiens	130-134	
25520135-3	2014	We aimed to explore the methylation status of MGMT gene among the North Eastern population where esophageal cancer incidence and exposure to carcinogens like nitrosamines is high.	Nitrosamines	158-170	O-6-methylguanine-DNA methyltransferase	Homo sapiens	46-50	
25520135-7	2014	Hypermethylation of MGMT gene was found to be influenced by environmental factors like betel quid and tobacco which contain potent carcinogens like nitrosamines.	Nitrosamines	148-160	O-6-methylguanine-DNA methyltransferase	Homo sapiens	20-24	
22994708-1	2012	The enzyme encoded by the MGMT gene is involved in the repair of alkylated lesions formed in DNA by carcinogenic nitrosamines.	Nitrosamines	113-125	O-6-methylguanine-DNA methyltransferase	Homo sapiens	26-30	
16007001-0	2005	The L84F and the I143V polymorphisms in the O6-methylguanine-DNA-methyltransferase (MGMT) gene increase human sensitivity to the genotoxic effects of the tobacco-specific nitrosamine carcinogen NNK.	Nitrosamines	171-182	O-6-methylguanine-DNA methyltransferase	Homo sapiens	44-82	
16007001-0	2005	The L84F and the I143V polymorphisms in the O6-methylguanine-DNA-methyltransferase (MGMT) gene increase human sensitivity to the genotoxic effects of the tobacco-specific nitrosamine carcinogen NNK.	Nitrosamines	171-182	O-6-methylguanine-DNA methyltransferase	Homo sapiens	84-88	
16007001-4	2005	We developed two novel genotyping techniques and used them, in conjunction with the mutagen-sensitivity assay, to test the hypothesis that the L84F and I143V cSNPs in the MGMT gene confer increased sensitivity to genetic damage induced by the alkylating tobacco-specific nitrosamine carcinogen NNK.	Nitrosamines	271-282	O-6-methylguanine-DNA methyltransferase	Homo sapiens	171-175	
12807758-1	2003	The development of esophageal squamous cell carcinoma (ESCC) has been linked to exposure to carcinogens such as nitrosamines that cause various alkyl DNA damages and O6-methylguanine-DNA methyltransferase (MGMT) is a primary defence against alkylation-induced mutagenesis and carcinogenesis.	Nitrosamines	112-124	O-6-methylguanine-DNA methyltransferase	Homo sapiens	206-210