PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26279158-1	2015	AIM: Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents.	Glutathione	28-39	glyoxalase 1	Mus musculus	5-17	
28623132-1	2017	Glyoxalase 1 (Glo1) is the first enzyme involved in glutathione-dependent detoxification of methylglyoxal, eventually generating d-lactate by the second enzyme glyoxalase 2 (Glo2).	Glutathione	52-63	glyoxalase 1	Mus musculus	0-12	
28623132-1	2017	Glyoxalase 1 (Glo1) is the first enzyme involved in glutathione-dependent detoxification of methylglyoxal, eventually generating d-lactate by the second enzyme glyoxalase 2 (Glo2).	Glutathione	52-63	glyoxalase 1	Mus musculus	14-18	
26279158-1	2015	AIM: Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents.	Glutathione	28-39	glyoxalase 1	Mus musculus	19-23	
26279158-1	2015	AIM: Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents.	Glutathione	28-39	glyoxalase 1	Mus musculus	157-161	
26279158-1	2015	AIM: Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents.	Glutathione	41-44	glyoxalase 1	Mus musculus	5-17	
26279158-1	2015	AIM: Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents.	Glutathione	41-44	glyoxalase 1	Mus musculus	19-23	
26279158-1	2015	AIM: Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents.	Glutathione	41-44	glyoxalase 1	Mus musculus	157-161	
26279158-3	2015	The aim of this study was to discover novel non-GSH analog GLOI inhibitors and analyze their binding mechanisms.	Glutathione	48-51	glyoxalase 1	Mus musculus	59-63	
26279158-12	2015	CONCLUSION: This work demonstrates a carboxyl group to be an important functional feature of non-GSH analog GLOI inhibitors.	Glutathione	97-100	glyoxalase 1	Mus musculus	108-112	
12605598-15	2003	The activities of two important enzymes, namely glyoxalase I and creatine kinase, which act upon glutathione plus methylglyoxal and creatine respectively, were also measured in different PMS.	Glutathione	97-108	glyoxalase 1	Mus musculus	48-60	
17368722-1	2007	Glutathione-related enzymes glyoxalase 1 and glutathione reductase 1 regulates anxiety in mice.	Glutathione	0-11	glyoxalase 1	Mus musculus	28-40	
17609286-7	2007	Because the cofactor for glyoxalase I, glutathione, is decreased in renal cortex of db/db mice, renal cortical glyoxalase I activity was measured in vitro with fixed amounts of exogenous glutathione.	Glutathione	39-50	glyoxalase 1	Mus musculus	25-37	
17609286-9	2007	These data indicate that diabetes-induced decreases in glyoxalase I activity are likely to be due to glutathione-dependent and -independent mechanisms and that increased expression of glyoxalase I may represent an insufficient adaptive response to increased methylglyoxal formation.	Glutathione	101-112	glyoxalase 1	Mus musculus	55-67	
7350914-7	1980	Mouse liver glyoxalase II is competitively inhibited by the substrate of glyoxalase I (the hemimercaptal of methylglyoxal and glutathione); the Ki is 0.3 mM.	Glutathione	126-137	glyoxalase 1	Mus musculus	12-24	
30628789-3	2019	GLO1 is a Zn2+-dependent enzyme that isomerizes a hemithioacetal, formed from glutathione and methylglyoxal, to a lactic acid thioester.	Glutathione	78-89	glyoxalase 1	Mus musculus	0-4