PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34801855-10	2022	Baicalein reduces the production of inflammatory mediators TNF-alpha, MIP-1, IL-6, and diminishes neutrophil influx and severity of endotoxin-mediated ALI.	baicalein	0-9	interleukin 6	Homo sapiens	77-81	
34152720-5	2021	Our results demonstrated that treatment with baicalein protects T98G cells from H2O2-induced damage, delays cell senescence, inhibits the secretion of SASP (IL-6, IL-8, TNF-alpha, CXCL1, and MMP-1), and inhibits SASP-related pathways NF-kappaB and JAK2/STAT1.	baicalein	45-54	interleukin 6	Homo sapiens	157-161	
33645093-10	2021	The molecular docking results showed that the main active components(quercetin, kaempferol, beta-sitosterol, luteolin, stigmasterol and baicalein) of Xuefu Zhuyu Decoction in the treatment of myocardial infarction had good binding properties with the core proteins IL6, ALB, VEGFA, TNF, MAPK3 and CASP3.	baicalein	136-145	interleukin 6	Homo sapiens	265-268	
25004875-4	2014	In addition, pretreatment with baicalein inhibited LPS-induced early (e.g., tumor necrosis factor-alpha (TNF-alpha) and interleukin-6) and late (e.g., high mobility group box 1 (HMGB1) pro-inflammatory cytokine release, inducible nitric oxide synthase (iNOS) expression and NO production.	baicalein	31-40	interleukin 6	Homo sapiens	120-133	
33496116-9	2020	The results of molecular docking showed that baicalein,berberine,licochalcone A and 6-gingerol had a high affinity with SRC,STAT3,TNF and IL6.	baicalein	45-54	interleukin 6	Homo sapiens	138-141	
33268707-5	2020	Moreover, baicalein suppressed the production of interleukin (IL)-6 and the metastatic potential of breast cancer cells both in vitro and in vivo.	baicalein	10-19	interleukin 6	Homo sapiens	49-67	
30072902-6	2018	The pharmacodynamic model was developed using a NLME modeling program Monolix  2016R1.The results showed that baicalein quickly suppressed release of TNF-alpha in a concentration-dependent manner, and consequently causing the diminution of IL-6 and iNOS/NO.	baicalein	110-119	interleukin 6	Homo sapiens	240-244	
33204288-12	2020	Molecular docking showed that quercetin, kaempferol, baicalein, and wogonin have good binding activity with IL6, VEGFA, EGFR, and NFKBIA targets.	baicalein	53-62	interleukin 6	Homo sapiens	108-111	
12873450-8	2003	Baicalin did not suppress IL-1beta-induced IL-6 and IL-8 production, but dexamethasone, baicalein, and wogonin, significantly suppressed IL-6 and IL-8 production.	baicalein	88-97	interleukin 6	Homo sapiens	137-141	
22284780-11	2012	Specifically, apiegenin, baicalein, curcumin, EGCG, genistein, luteolin, oridonin, quercetin, and wogonin repress NF-kappaB (NF-kappaB, a proinflammatory transcription factor) and inhibit proinflammatory cytokines such as TNF-alpha and IL-6.	baicalein	25-34	interleukin 6	Homo sapiens	236-240	
19878271-5	2010	In the present study of four myeloma cell lines, namely U266, NOP2, AMO1, and ILKM2, we demonstrated that baicalein not only inhibited IL-6-mediated phosphorylation of signaling proteins, such as Jak, STAT3, MAPK, and Akt, but also inhibited the expression of their target genes, such as bcl-xl.	baicalein	106-115	interleukin 6	Homo sapiens	135-139	
19878271-10	2010	Our results demonstrate that baicalein is a potent inhibitor of protein phosphorylation induced by IL-6, and thus may be a useful agent for the treatment of MM.	baicalein	29-38	interleukin 6	Homo sapiens	99-103