PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33417255-5	2021	Using Annexin V/propidium iodide staining, a significant increase in apoptosis was found after chrysophanol treatment on HeLa cells, and this process was mediated by caspases 3/7 with a clear inactivation of the antiapoptotic Bcl-2 family protein.	Propidium	16-32	caspase 3	Homo sapiens	166-178	
32495168-4	2020	Fluorescence of active caspases 3 and 7 and changes in nuclear DNA in cells in the presence of CyAm were detected by using fluorochrome-labeled inhibitor of caspases (FLICA) and Hoechst and propidium iodide reagents.	Propidium	190-206	caspase 3	Homo sapiens	23-39	
32382956-8	2020	Activation of caspase-3, indicative of apoptosis, was seen both for cathinones and METH, and confirmed by annexin V and propidium iodide positive staining.	Propidium	120-136	caspase 3	Homo sapiens	14-23	
32606957-11	2020	Activation of apoptosis/necrosis was confirmed by annexin V/propidium iodide double staining, which showed increasing levels of active caspase 3, cleaved poly(ADP-ribose) polymerase and the RIP1-RIP3-MLKL complex.	Propidium	60-76	caspase 3	Homo sapiens	135-144	
30602587-6	2019	Caspase-3 protein expression was also significantly decreased in U373MG cells indicating IDE-induced apoptosis that was confirmed by flow cytometric Annexin V/propidium iodide staining.	Propidium	159-175	caspase 3	Homo sapiens	0-9	
31336786-5	2019	Treatment of DMC led to the apoptosis of PANC-1 by caspase-3 activation as revealed by annexin-V/propidium iodide double-staining.	Propidium	97-113	caspase 3	Homo sapiens	51-60	
30014921-18	2018	Inhibition of FAK enzyme led to a significant increase in the level of active caspase-3, compared to control (11.35 folds), accumulation of cells in pre-G1 phase and annexin-V and propidium iodide staining in addition to cell cycle arrest at G2/M phase indicating that cell death proceeded through an apoptotic mechanism.	Propidium	180-196	caspase 3	Homo sapiens	78-87	
17532820-7	2007	Furthermore, the caspase-3 expression was determined by a immunocytochemical staining method before and after treatment with rosiglitazone and 15-d-PGJ2 for 48 h. The cell cycles were measured by flow cytometric analysis using propidium iodide (PI).	Propidium	227-243	caspase 3	Homo sapiens	17-26	
19235896-4	2009	Preincubation with the caspase-9 inhibitor z-LEHD-fmk, the caspase-3 inhibitor z-DEVD-fmk, or the specific pan-caspase inhibitor Q-VD-oph decreased the percentage of propidium iodide-positive neurons (52.5% +/- 3.1%, 39.4% +/- 3.5%, 44.6% +/- 3%, respectively, vs. 65% +/- 3% in glutamate + vehicle).	Propidium	166-182	caspase 3	Homo sapiens	59-68	
15237193-4	2004	Activation of caspase-3 and fractin was measured by counting immunohistochemically stained cells and by flow cytometry with propidium iodide (detection of the apoptosis indicating a sub-G1 peak).	Propidium	124-140	caspase 3	Homo sapiens	14-23	
10617114-10	2000	Double labeling with propidium iodide to detect chromatin condensation indicated that affinity-labeled caspase-3-like proteases were specifically expressed in apoptotic cells.	Propidium	21-37	caspase 3	Homo sapiens	103-112