PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12946602-0	2003	NMDA-NR1 and -NR2B subunits mRNA expression in the hippocampus of rats tolerant to Diazepam.	Diazepam	83-91	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	5-8	
30521-0	1978	Benzodiasepine and neurotransmitter receptor binding in rat brain after chronic administration of diazepam or phenobarbital.	Diazepam	98-106	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	19-44	
15081382-5	2004	Our results demonstrate that the development of tolerance to the hypolocomotive effect of diazepam, along with the increased hippocampal synaptic plasticity and the associated over expression of the mRNA NR1 and NR2B N-methyl-D-aspartate receptor subunits, were blocked by previous MK-801 administration.	Diazepam	90-98	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	204-207	
22366010-6	2012	The model group showed significantly diminished GABAA receptor-positive cells and increased NMDAR1-positive cells, which were improved by diazepam and ASF at the medium dose.	Diazepam	138-146	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	92-98	
12946602-4	2003	The results of the present investigation show that the development of tolerance to hypolocomotor action of DZ (5 mg/kg/day) for 4 days results in a significant increase in the hybridization signals for mRNA for N-methyl-D-aspartate (NMDA) glutamatergic receptor NR1 and NR2B subunits in the hippocampal dentate gyrus.	Diazepam	107-109	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	262-265	
9543260-2	1998	The protein levels of the NR1 and NR2B, but not NR2A, subunits were significantly increased in diazepam-withdrawn rats compared to those in control rats.	Diazepam	95-103	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	26-29	
9543260-3	1998	Therefore, an increase in the NR1 and NR2B subunit proteins may be responsible for both the previously observed upregulation of [3H]dizocilpine binding in the cerebral cortex and the appearance of diazepam withdrawal signs.	Diazepam	197-205	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	30-33