PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22366010-6 2012 The model group showed significantly diminished GABAA receptor-positive cells and increased NMDAR1-positive cells, which were improved by diazepam and ASF at the medium dose. Diazepam 138-146 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 92-98 30521-0 1978 Benzodiasepine and neurotransmitter receptor binding in rat brain after chronic administration of diazepam or phenobarbital. Diazepam 98-106 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 19-44 15081382-5 2004 Our results demonstrate that the development of tolerance to the hypolocomotive effect of diazepam, along with the increased hippocampal synaptic plasticity and the associated over expression of the mRNA NR1 and NR2B N-methyl-D-aspartate receptor subunits, were blocked by previous MK-801 administration. Diazepam 90-98 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 204-207 12946602-0 2003 NMDA-NR1 and -NR2B subunits mRNA expression in the hippocampus of rats tolerant to Diazepam. Diazepam 83-91 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 5-8 12946602-4 2003 The results of the present investigation show that the development of tolerance to hypolocomotor action of DZ (5 mg/kg/day) for 4 days results in a significant increase in the hybridization signals for mRNA for N-methyl-D-aspartate (NMDA) glutamatergic receptor NR1 and NR2B subunits in the hippocampal dentate gyrus. Diazepam 107-109 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 262-265 9543260-2 1998 The protein levels of the NR1 and NR2B, but not NR2A, subunits were significantly increased in diazepam-withdrawn rats compared to those in control rats. Diazepam 95-103 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 26-29 9543260-3 1998 Therefore, an increase in the NR1 and NR2B subunit proteins may be responsible for both the previously observed upregulation of [3H]dizocilpine binding in the cerebral cortex and the appearance of diazepam withdrawal signs. Diazepam 197-205 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 30-33