PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7929453-9	1994	Thus, the subunit combinations alpha 1 beta 2 gamma 2 and alpha 2 beta 3 gamma 2 represent two main GABAA receptor subtypes, which together amount to 75-85% of the diazepam-sensitive GABAA receptors.	Diazepam	164-172	adrenoceptor alpha 1D	Homo sapiens	31-38	
15926867-1	2005	Non-selective benzodiazepine (BZ) binding-site full agonists, exemplified by diazepam, act by enhancing the inhibitory effects of GABA at GABA(A) receptors containing either an alpha1, -2, -3 or -5 subunit.	Diazepam	77-85	adrenoceptor alpha 1D	Homo sapiens	177-197	
11100148-3	2000	Here we show that, with low concentrations of GABA, diazepam produces a biphasic potentiation for the alpha1beta2gamma2-receptor channel, with distinct components in the nanomolar and micromolar concentration ranges.	Diazepam	52-60	adrenoceptor alpha 1D	Homo sapiens	102-119	
8592140-6	1996	The alpha 1 subunit contributes the high-affinity binding of [3H]Ro 15-1788 (flumazenil) and the diazepam-sensitive binding of [3H]Ro 15-4513.	Diazepam	97-105	adrenoceptor alpha 1D	Homo sapiens	4-11	
14660012-2	2003	Exposure (48 and/or 96 h) of human embryonic kidney (HEK 293) cells stably expressing recombinant alpha1beta2gamma2s GABA(A) receptors for gamma-aminobutyric (GABA, 1 mM) and muscimol (100 microM), but not for diazepam (1 microM), enhanced the maximum number (B(max)) of [3H]flunitrazepam binding sites without affecting their affinity (K(d)).	Diazepam	210-218	adrenoceptor alpha 1D	Homo sapiens	98-115	
12494402-10	2003	Diazepam with affinity for alpha1, alpha2, alpha3, and alpha5 subunits inhibited the binding in all brain regions.	Diazepam	0-8	adrenoceptor alpha 1D	Homo sapiens	27-61	
11306694-6	2001	Of the diazepam-sensitive GABA(A) receptors (alpha1, alpha2, alpha3, alpha5), alpha5 showed the most divergence, being discriminated by zolpidem in terms of very low affinity, and CL218,872 and CGS9895 with different efficacies.	Diazepam	7-15	adrenoceptor alpha 1D	Homo sapiens	45-51	
10728882-10	2000	Cells transfected with alpha1 and gamma2S cDNAs displayed small diazepam and loreclezole responsive GABA-activated currents.	Diazepam	64-72	adrenoceptor alpha 1D	Homo sapiens	23-41	
8145733-7	1994	The apparent potency of GABA was increased 2-fold by diazepam with alpha 1 beta 2 gamma 2 receptors, 3-fold with alpha 3 beta 2 gamma 2 receptors, and 5-fold with alpha 1 alpha 3 beta 2 gamma 2 receptors.	Diazepam	53-61	adrenoceptor alpha 1D	Homo sapiens	67-89	
8145733-7	1994	The apparent potency of GABA was increased 2-fold by diazepam with alpha 1 beta 2 gamma 2 receptors, 3-fold with alpha 3 beta 2 gamma 2 receptors, and 5-fold with alpha 1 alpha 3 beta 2 gamma 2 receptors.	Diazepam	53-61	adrenoceptor alpha 1D	Homo sapiens	67-74	
17805947-4	2008	On the other hand, the docking of diazepam to alpha1/gamma2 interface revealed five multi-member conformational clusters in the binding site and model 1 seemed to represent the correct orientation of diazepam in the binding site.	Diazepam	34-42	adrenoceptor alpha 1D	Homo sapiens	46-59	
7681869-7	1993	Whole-cell currents recorded from cells coexpressing alpha 1 beta 1 gamma 2S subunits were three to four times larger than those recorded from cells coexpressing alpha 1 beta 1 subunits, and they were always enhanced by coapplied diazepam.	Diazepam	230-238	adrenoceptor alpha 1D	Homo sapiens	53-60	
7681869-7	1993	Whole-cell currents recorded from cells coexpressing alpha 1 beta 1 gamma 2S subunits were three to four times larger than those recorded from cells coexpressing alpha 1 beta 1 subunits, and they were always enhanced by coapplied diazepam.	Diazepam	230-238	adrenoceptor alpha 1D	Homo sapiens	162-169	
29138471-3	2017	In the absence of alpha1 subunits, a receptor was formed that was gated by GABA and modulated by diazepam similarly.	Diazepam	97-105	adrenoceptor alpha 1D	Homo sapiens	18-24	
29138471-8	2017	Thus, the beta2 subunit can take over the role of the alpha1 subunit for the formation of both sites, its minus side for the GABA binding site and its plus side for the diazepam binding site.	Diazepam	169-177	adrenoceptor alpha 1D	Homo sapiens	54-60	
17805947-4	2008	On the other hand, the docking of diazepam to alpha1/gamma2 interface revealed five multi-member conformational clusters in the binding site and model 1 seemed to represent the correct orientation of diazepam in the binding site.	Diazepam	200-208	adrenoceptor alpha 1D	Homo sapiens	46-59	
17377772-3	2007	Human embryonic kidney (HEK 293) cells stably expressing recombinant alpha1beta2gamma2s GABA(A) receptors were exposed for 72 h to a high concentration of diazepam (50 microM) in the absence or presence of other drugs.	Diazepam	155-163	adrenoceptor alpha 1D	Homo sapiens	69-86	
17087982-2	2007	Most 1,4-BZs like diazepam recognize all GABA(A)/BZ receptors containing the alpha1-3 or alpha5 together with any beta and the gamma2 subunit.	Diazepam	18-26	adrenoceptor alpha 1D	Homo sapiens	77-85