PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24802331-2 2014 This issue has been addressed in a number of molecular imaging studies by positron emission tomography or single-photon emission computed tomography of serotonin reuptake sites (5-HTT) in the brain of patients with MDD, with strikingly disparate conclusions. Serotonin 152-161 huntingtin Homo sapiens 180-183 25054562-6 2014 Importantly the expression of mRNAs of huntingtin is upregulated by repeated applications of serotonin, a modulatory transmitter released during learning in Aplysia. Serotonin 93-102 huntingtin Homo sapiens 39-49 25054562-7 2014 Furthermore, we find that huntingtin expression levels are critical, not only in presynaptic sensory neurons, but also in the postsynaptic motor neurons for serotonin-induced long-term facilitation at the sensory-to-motor neuron synapse of the Aplysia gill-withdrawal reflex. Serotonin 157-166 huntingtin Homo sapiens 26-36 16414028-8 2006 High concentrations of 5-HTT-positive fibers in the central nucleus indicate that tight regulation of serotonin is critical in modulating fear responses mediated by this nucleus. Serotonin 102-111 huntingtin Homo sapiens 25-28 18036835-3 2008 Of the biomarkers in the serotonin system, serotonin(1A) (5-HT(1A)) receptor is implicated in depression, and anxiety and serotonin transporter (5-HTT) is a target for selective serotonin reuptake inhibitors, psychotropic drugs used in the treatment of these disorders. Serotonin 25-34 huntingtin Homo sapiens 147-150 18036835-9 2008 Sex differences in 5-HT(1A) receptor and 5-HTT BP(ND) may reflect biological distinctions in the serotonin system contributing to sex differences in the prevalence of psychiatric disorders such as depression and anxiety. Serotonin 97-106 huntingtin Homo sapiens 43-46 16856124-2 2006 The serotonin transporter (HTT) regulates the availability of serotonin by reuptake of the neurotransmitter from the synaptic cleft. Serotonin 4-13 huntingtin Homo sapiens 27-30 23601559-3 2013 Serotonin (5-HT) has been shown to be involved in PH by inducing PASMC proliferation through the activation of 5-HT1B receptors (5-HT1BR) and 5-HT transporter (5-HTT). Serotonin 0-9 huntingtin Homo sapiens 162-165 23570994-3 2013 We hypothesized that ozone exposure alters the normal pattern of serotonin, its transporter (5-HTT), and two key receptors (5-HT2A and 5-HT4), a pathway involved in postnatal airway neural, epithelial, and immune processes. Serotonin 65-74 huntingtin Homo sapiens 95-98 19756523-1 2011 BACKGROUND: The serotonin transporter (5-HTT) plays a critical role in the regulation of serotonin neurotransmission and has been implicated in the pathophysiology of major depression. Serotonin 16-25 huntingtin Homo sapiens 41-44 18440664-1 2008 The serotonin (5-hydroxytryptamine, or 5-HT) transporters (5-HTT) are target-sites for commonly used antidepressants. Serotonin 4-13 huntingtin Homo sapiens 61-64 18440664-1 2008 The serotonin (5-hydroxytryptamine, or 5-HT) transporters (5-HTT) are target-sites for commonly used antidepressants. Serotonin 15-34 huntingtin Homo sapiens 61-64 18622081-2 2008 In particular, the neurotransmitter serotonin (5-hydroxytryptamine [5-HT]) has been hypothesized to play a role in skeletal metabolism via its transporter (5-HTT). Serotonin 36-45 huntingtin Homo sapiens 158-161 18622081-2 2008 In particular, the neurotransmitter serotonin (5-hydroxytryptamine [5-HT]) has been hypothesized to play a role in skeletal metabolism via its transporter (5-HTT). Serotonin 47-66 huntingtin Homo sapiens 158-161 16414028-9 2006 High concentrations of 5-HTT-labeled fibers in the intercalated islands and parvicellular basal nucleus/paralaminar nucleus, which contain immature -appearing neurons, suggest a potential trophic role for serotonin in these subregions. Serotonin 205-214 huntingtin Homo sapiens 25-28 15583118-13 2004 The magnitude of regional 5-HTT BP can provide a vulnerability to low levels of extracellular serotonin and symptoms of extremely negativistic dysfunctional attitudes. Serotonin 94-103 huntingtin Homo sapiens 28-31 16616982-2 2006 The serotonin transporter (5-HTT) may play an important role in the termination of serotonergic neurotransmission by serotonin (5-HT) uptaking into presynaptic neurons and representing as an initial action site for selective 5-HTT reuptake inhibitors (SSRI). Serotonin 4-13 huntingtin Homo sapiens 29-32 16616982-2 2006 The serotonin transporter (5-HTT) may play an important role in the termination of serotonergic neurotransmission by serotonin (5-HT) uptaking into presynaptic neurons and representing as an initial action site for selective 5-HTT reuptake inhibitors (SSRI). Serotonin 4-13 huntingtin Homo sapiens 227-230 11443529-1 2001 The promoter polymorphism of the serotonin transporter gene (HTT, locus SLC6A4) is of special interest in autism given the well-replicated platelet hyperserotonemia of autism, treatment effects of serotonin reuptake inhibitors, and the role of serotonin in limbic functioning and neurodevelopment. Serotonin 33-42 huntingtin Homo sapiens 61-64 27567324-7 2016 The lack of correlation between 5-HT1A and 5-HTT binding observed in the current study may be due to the different temporal responsiveness of regulatory processes controlling the somatodendritic 5-HT1A receptor and 5-HTT in response to changing availability of intrasynaptic serotonin. Serotonin 275-284 huntingtin Homo sapiens 217-220 11443529-1 2001 The promoter polymorphism of the serotonin transporter gene (HTT, locus SLC6A4) is of special interest in autism given the well-replicated platelet hyperserotonemia of autism, treatment effects of serotonin reuptake inhibitors, and the role of serotonin in limbic functioning and neurodevelopment. Serotonin 197-206 huntingtin Homo sapiens 61-64 9322235-3 1997 SRIs block the reuptake of serotonin (5-HT) into the presynaptic neuron, a process mediated by the serotonin transporter (5-HTT). Serotonin 27-36 huntingtin Homo sapiens 124-127 27567324-1 2016 The serotonin neurotransmitter system is modulated in part by the uptake of synaptically released serotonin (5-HT) by the serotonin transporter (5-HTT), and by specific serotonin autoreceptors such as the somatodendritic 5-HT1A receptor, which can limit serotonin neuron depolarization. Serotonin 4-13 huntingtin Homo sapiens 147-150 32463584-4 2020 For antidepressants, the clinical threshold of serotonin transporter (5-HTT) occupancy is reported to be 70%-80% although the relation between the side effect and 5-HTT occupancy has not yet been established. Serotonin 47-56 huntingtin Homo sapiens 72-75 27567324-1 2016 The serotonin neurotransmitter system is modulated in part by the uptake of synaptically released serotonin (5-HT) by the serotonin transporter (5-HTT), and by specific serotonin autoreceptors such as the somatodendritic 5-HT1A receptor, which can limit serotonin neuron depolarization. Serotonin 98-107 huntingtin Homo sapiens 147-150 27567324-1 2016 The serotonin neurotransmitter system is modulated in part by the uptake of synaptically released serotonin (5-HT) by the serotonin transporter (5-HTT), and by specific serotonin autoreceptors such as the somatodendritic 5-HT1A receptor, which can limit serotonin neuron depolarization. Serotonin 98-107 huntingtin Homo sapiens 147-150 27567324-1 2016 The serotonin neurotransmitter system is modulated in part by the uptake of synaptically released serotonin (5-HT) by the serotonin transporter (5-HTT), and by specific serotonin autoreceptors such as the somatodendritic 5-HT1A receptor, which can limit serotonin neuron depolarization. Serotonin 98-107 huntingtin Homo sapiens 147-150