PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33593821-4 2021 Ritanserin, an inhibitor of diacylglycerol kinase alpha (DGKA), was identified as a selective inhibitor of proliferation of Tsc2-/- MEFs, with no impact on Tsc2+/+ MEFs. Ritanserin 0-10 TSC complex subunit 2 Mus musculus 124-128 33593821-6 2021 PA levels were increased 5-fold in Tsc2-/- MEFs compared to Tsc2+/+ MEFs, and treatment of Tsc2-/- MEFs with ritanserin led to depletion of PA as well as rewiring of phospholipid metabolism. Ritanserin 109-119 TSC complex subunit 2 Mus musculus 35-39 33593821-6 2021 PA levels were increased 5-fold in Tsc2-/- MEFs compared to Tsc2+/+ MEFs, and treatment of Tsc2-/- MEFs with ritanserin led to depletion of PA as well as rewiring of phospholipid metabolism. Ritanserin 109-119 TSC complex subunit 2 Mus musculus 60-64 33593821-6 2021 PA levels were increased 5-fold in Tsc2-/- MEFs compared to Tsc2+/+ MEFs, and treatment of Tsc2-/- MEFs with ritanserin led to depletion of PA as well as rewiring of phospholipid metabolism. Ritanserin 109-119 TSC complex subunit 2 Mus musculus 60-64 33593821-8 2021 Ritanserin decreased macropinocytic uptake of albumin, limited the number of lysosomes, and reduced lysosomal activity in Tsc2-/- MEFs. Ritanserin 0-10 TSC complex subunit 2 Mus musculus 122-126