PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8730981-3 1996 To investigate the potential of NEF and its metabolites to interfere with the metabolism of other drugs, we tested these compounds for their ability to alter dextromethorphan (DMO) O-demethylation to dextrorphan (DOP; an index reaction for CYP2D6) and N-demethylation to 3-methoxy morphinan (MEM, a recently proposed index reaction of CYP3A3/4). Dextrorphan 200-211 S100 calcium binding protein B Homo sapiens 32-35 8730981-3 1996 To investigate the potential of NEF and its metabolites to interfere with the metabolism of other drugs, we tested these compounds for their ability to alter dextromethorphan (DMO) O-demethylation to dextrorphan (DOP; an index reaction for CYP2D6) and N-demethylation to 3-methoxy morphinan (MEM, a recently proposed index reaction of CYP3A3/4). Dextrorphan 213-216 S100 calcium binding protein B Homo sapiens 32-35