PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17922191-8	2007	MMC treatment resulted in higher caspase-8 enzymatic activity and apoptosis and could be synergistically enhanced by co-stimulation with interferon-alpha (IFNalpha) via independent transcriptional mechanisms.	Mitomycin	0-3	interferon alpha 1	Homo sapiens	155-163	
7152202-4	1982	In combinations of Hu IFN-alpha with anticancer agents such as bleomycin, mitomycin C, and cytosine arabinoside in certain concentration ranges, antagonism was noticed when Hu IFN-alpha and anticancer agents were added simultaneously to the cell culture.	Mitomycin	74-85	interferon alpha 1	Homo sapiens	22-31	
7152202-4	1982	In combinations of Hu IFN-alpha with anticancer agents such as bleomycin, mitomycin C, and cytosine arabinoside in certain concentration ranges, antagonism was noticed when Hu IFN-alpha and anticancer agents were added simultaneously to the cell culture.	Mitomycin	74-85	interferon alpha 1	Homo sapiens	176-185	
17652735-12	2007	Caspase-8, caspase-3, and broad caspase inhibitors, but not caspase-9 inhibitor, inhibited MMC-induced cell death in nonpretreated and IFN-pretreated cells.	Mitomycin	91-94	interferon alpha 1	Homo sapiens	135-138	
17652735-13	2007	CONCLUSIONS: IFN-alpha and IFN-gamma enhance the susceptibility of HTFs to MMC-induced cell death through a Fas-mediated and a caspase-3-dependent pathway.	Mitomycin	75-78	interferon alpha 1	Homo sapiens	13-22	
17652735-14	2007	Pretreatment with IFN primed HTFs to MMC, providing a potential means for initially slowing the healing response with IFN and subsequently terminating fibroblast activity through MMC-induced cell death.	Mitomycin	37-40	interferon alpha 1	Homo sapiens	18-21	
17652735-14	2007	Pretreatment with IFN primed HTFs to MMC, providing a potential means for initially slowing the healing response with IFN and subsequently terminating fibroblast activity through MMC-induced cell death.	Mitomycin	37-40	interferon alpha 1	Homo sapiens	118-121	
2444657-4	1987	However, the effect of IFN in the presence of ADM or MMC was additive.	Mitomycin	53-56	interferon alpha 1	Homo sapiens	23-26	
17652735-1	2007	PURPOSE: To investigate the effect of interferon (IFN)-alpha and IFN-gamma pretreatment on mitomycin C (MMC)-induced cell death in human Tenon fibroblasts (HTFs) and the mechanisms by which IFN-alpha and IFN-gamma modulate the susceptibility of HTFs to MMC.	Mitomycin	91-102	interferon alpha 1	Homo sapiens	38-60	
1346369-8	1992	The suppressive effects of IFN-alpha were overcome by addition of immobilized anti-CD3-preactivated T cells that had been treated with mitomycin C, but not by the addition of fresh T cells or soluble factors produced by activated T cells.	Mitomycin	135-146	interferon alpha 1	Homo sapiens	27-36