PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9876011-3 1998 In the present study, therefore, ras p21 protein expression was examined in in vitro cultures of human lymphocytes treated with mitomycin C and in the human colon adenocarcinoma Caco-2 cell line treated with doxorubicin with and without deferoxamine. Mitomycin 128-139 H3 histone pseudogene 16 Homo sapiens 37-40 20235278-6 2010 Treatment Ki67p-GFP expressing HT1080 cells with mitomycin C, an antineoplastic agent, induces P21 and P27 expression, G(1)/S/G(2)M block and attenuates Ki67p activity. Mitomycin 49-60 H3 histone pseudogene 16 Homo sapiens 95-98 12468545-6 2003 Basal levels as well as Vp16- or mitomycin C-stimulated levels of p53 and p21 protein were decreased in the catalase-overexpressing cells as compared with control cells; however, p53 mRNA levels were not decreased by catalase. Mitomycin 33-44 H3 histone pseudogene 16 Homo sapiens 74-77 11462153-11 2001 Western blot analysis of p53 and p21 revealed a gradual increase in the level of these proteins when RPE cells were exposed to increasing concentrations of MMC. Mitomycin 156-159 H3 histone pseudogene 16 Homo sapiens 33-36 18806879-10 2008 CONCLUSIONS: These results indicate that mitomycin-induced cellular apoptosis in corneal endothelial cells may be mediated through caspase-8, caspase-9, and the mitochondrial regulated pathways as well as through upregulation of p53-dependent and p21-dependent signal transduction pathways. Mitomycin 41-50 H3 histone pseudogene 16 Homo sapiens 247-250 11299739-6 2001 We therefore concluded that immunohistochemical studies for p53 and p21 were useful for predicting the chemosensitivities of colon and gastric cancer to MMC and 5-FU. Mitomycin 153-156 H3 histone pseudogene 16 Homo sapiens 68-71 9876011-5 1998 Increases in p21 protein levels were seen with mitomycin C but no clear response was seen with doxorubicin. Mitomycin 47-58 H3 histone pseudogene 16 Homo sapiens 13-16