PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18806879-10	2008	CONCLUSIONS: These results indicate that mitomycin-induced cellular apoptosis in corneal endothelial cells may be mediated through caspase-8, caspase-9, and the mitochondrial regulated pathways as well as through upregulation of p53-dependent and p21-dependent signal transduction pathways.	Mitomycin	41-50	H3 histone pseudogene 16	Homo sapiens	247-250	
12468545-6	2003	Basal levels as well as Vp16- or mitomycin C-stimulated levels of p53 and p21 protein were decreased in the catalase-overexpressing cells as compared with control cells; however, p53 mRNA levels were not decreased by catalase.	Mitomycin	33-44	H3 histone pseudogene 16	Homo sapiens	74-77	
20235278-6	2010	Treatment Ki67p-GFP expressing HT1080 cells with mitomycin C, an antineoplastic agent, induces P21 and P27 expression, G(1)/S/G(2)M block and attenuates Ki67p activity.	Mitomycin	49-60	H3 histone pseudogene 16	Homo sapiens	95-98	
11462153-11	2001	Western blot analysis of p53 and p21 revealed a gradual increase in the level of these proteins when RPE cells were exposed to increasing concentrations of MMC.	Mitomycin	156-159	H3 histone pseudogene 16	Homo sapiens	33-36	
11299739-6	2001	We therefore concluded that immunohistochemical studies for p53 and p21 were useful for predicting the chemosensitivities of colon and gastric cancer to MMC and 5-FU.	Mitomycin	153-156	H3 histone pseudogene 16	Homo sapiens	68-71	
9876011-3	1998	In the present study, therefore, ras p21 protein expression was examined in in vitro cultures of human lymphocytes treated with mitomycin C and in the human colon adenocarcinoma Caco-2 cell line treated with doxorubicin with and without deferoxamine.	Mitomycin	128-139	H3 histone pseudogene 16	Homo sapiens	37-40	
9876011-5	1998	Increases in p21 protein levels were seen with mitomycin C but no clear response was seen with doxorubicin.	Mitomycin	47-58	H3 histone pseudogene 16	Homo sapiens	13-16