PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15634021-5	2005	They displayed also a partial agonist profile in a human 5-HT(1A) [(35)S]GTP gamma S binding assay, suggesting their potential use as atypical antipsychotic agents.	Guanosine Triphosphate	73-76	5-hydroxytryptamine receptor 1A	Homo sapiens	57-64	
9402034-0	1997	Stimulated [35S]GTP gamma S binding by 5-HT1A receptor agonists in recombinant cell lines.	Guanosine Triphosphate	16-19	5-hydroxytryptamine receptor 1A	Homo sapiens	39-54	
11755134-2	2001	Na(+)-dependent [35S] GTP gamma S binding to membranes from human epithelioid carcinoma (HeLa) cells, expressing 500 fmol/mg protein of h5-HT(1A) receptor (HA7 cells), appears suitable to characterize not only agonist and antagonist properties of 5-HT(1A) receptor ligands, but also inverse agonist properties.	Guanosine Triphosphate	22-25	5-hydroxytryptamine receptor 1A	Homo sapiens	137-154	
9402034-8	1997	Each of the [35S]GTP gamma S binding responses was mediated by a 5-HT1A receptor as indicated by the competitive blockade by WAY100635 and spiperone.	Guanosine Triphosphate	17-20	5-hydroxytryptamine receptor 1A	Homo sapiens	65-80	
8831111-0	1996	S 15535 and WAY 100,635 antagonise 5-HT-stimulated [35S]GTP gamma S binding at cloned human 5-HT1A receptors.	Guanosine Triphosphate	56-59	5-hydroxytryptamine receptor 1A	Homo sapiens	92-98	
18289523-1	2008	The effect of chronic citalopram or escitalopram administration on 5-HT1A receptor function in the dorsal raphe nucleus was determined by measuring [35S]GTP gamma S binding stimulated by the 5-HT1A receptor agonist (R)-(+)-8-OH-DPAT (1nM-10 microM).	Guanosine Triphosphate	153-156	5-hydroxytryptamine receptor 1A	Homo sapiens	67-82	
18289523-1	2008	The effect of chronic citalopram or escitalopram administration on 5-HT1A receptor function in the dorsal raphe nucleus was determined by measuring [35S]GTP gamma S binding stimulated by the 5-HT1A receptor agonist (R)-(+)-8-OH-DPAT (1nM-10 microM).	Guanosine Triphosphate	153-156	5-hydroxytryptamine receptor 1A	Homo sapiens	191-206	
9059863-0	1997	Characterisation of a cloned human 5-HT1A receptor cell line using [35S]GTP gamma S binding.	Guanosine Triphosphate	72-75	5-hydroxytryptamine receptor 1A	Homo sapiens	35-50	
1680719-4	1991	This effect of GTP can be attributed to decreased binding of the radioligand to the 5-HT1A receptors.	Guanosine Triphosphate	15-18	5-hydroxytryptamine receptor 1A	Homo sapiens	84-90	
1680719-9	1991	Nucleotides decrease the binding of [3H]rauwolscine to the 5-HT1A receptors with an order of potencies (i.e. GTP gamma S greater than GPP(NH)P much greater than GDP greater than GTP much greater than ATP) that is typical for nucleotide-mediated receptor-G protein dissociation.	Guanosine Triphosphate	109-112	5-hydroxytryptamine receptor 1A	Homo sapiens	59-65	
1680719-9	1991	Nucleotides decrease the binding of [3H]rauwolscine to the 5-HT1A receptors with an order of potencies (i.e. GTP gamma S greater than GPP(NH)P much greater than GDP greater than GTP much greater than ATP) that is typical for nucleotide-mediated receptor-G protein dissociation.	Guanosine Triphosphate	178-181	5-hydroxytryptamine receptor 1A	Homo sapiens	59-65	
1824956-10	1991	Our findings suggest that there are GTP-sensitive 5-HT1A sites in the human brain and that selective increases in GTP-sensitive 5-HT1A sites in the prefrontal and temporal cortices of schizophrenics relate to the pathophysiology of schizophrenia.	Guanosine Triphosphate	36-39	5-hydroxytryptamine receptor 1A	Homo sapiens	50-56	
1824956-10	1991	Our findings suggest that there are GTP-sensitive 5-HT1A sites in the human brain and that selective increases in GTP-sensitive 5-HT1A sites in the prefrontal and temporal cortices of schizophrenics relate to the pathophysiology of schizophrenia.	Guanosine Triphosphate	114-117	5-hydroxytryptamine receptor 1A	Homo sapiens	128-134	
3013203-4	1986	GMP and adenine nucleotides had a minimal effect on [3H]-8-OH-DPAT binding at concentrations less than 10(-3) M. Saturation experiments demonstrated that 10(-4) M GTP increased the KD of [3H]-8-OH-DPAT for 5-HT1A binding sites (0.79 to 2.7 nM) without changing the number of binding sites (1.98 to 1.93 pmoles/g tissue).	Guanosine Triphosphate	163-166	5-hydroxytryptamine receptor 1A	Homo sapiens	206-212	
20041669-4	2010	[(35)S]GTP gamma S function assays on 5-HT(1A) receptor indicated that aporphines 17 and 20 were partial agonists, while trans-19 behaved as a high efficacy full antagonist and cis-19 was a full agonist.	Guanosine Triphosphate	7-10	5-hydroxytryptamine receptor 1A	Homo sapiens	38-55