PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30930748-6 2019 Moreover, cofilin activates phagocytosis by advancing the remodeling of actin filaments (i.e., existing filaments disassemble and new filaments assemble in a new configuration), causing filopodia/lamellipodia to protrude, and furthermore, Galectin-3 (formally named MAC-2) activates phagocytosis by enhancing K-Ras.GTP/PI3K signaling that leads to actin/myosin-based contraction, causing filopodia/lamellipodia to retract. Guanosine Triphosphate 315-318 cofilin 1 Homo sapiens 10-17 31396321-7 2019 Moreover, it promoted the expression of downstream Rho GTP signaling molecules, including PAK 1, ROCK 2, LIMK 1 and Cofilin. Guanosine Triphosphate 55-58 cofilin 1 Homo sapiens 116-123 20610540-6 2010 Basal phosphorylation of cofilin(Ser3) is mediated by active/GTP-bound Rho and downstream protein kinases; LHR signaling promotes a decrease in active/GTP-bound Rho by a PKA-dependent mechanism. Guanosine Triphosphate 61-64 cofilin 1 Homo sapiens 25-32 20610540-6 2010 Basal phosphorylation of cofilin(Ser3) is mediated by active/GTP-bound Rho and downstream protein kinases; LHR signaling promotes a decrease in active/GTP-bound Rho by a PKA-dependent mechanism. Guanosine Triphosphate 151-154 cofilin 1 Homo sapiens 25-32 8037689-11 1994 Experiments with electropermeabilized platelets showed that dephosphorylation of cofilin could be stimulated by guanosine 5"-[gamma-thio]triphosphate (GTP[S]) in the absence of Ca2+ or by a free Ca2+ concentration of 10 microM. Guanosine Triphosphate 151-154 cofilin 1 Homo sapiens 81-88 8037689-13 1994 Our results add cofilin to the actin-binding proteins that may regulate the platelet cytoskeleton, and suggest that platelet cofilin can be activated by dephosphorylation reactions initiated either by a GTP-binding protein or Ca2+. Guanosine Triphosphate 203-206 cofilin 1 Homo sapiens 125-132