PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14965348-2	2004	This phenomenon reflects reversible deformation of the adenine nucleotide translocase, the loss of its native gating properties and the stabilization of the deformed state by cyclophilin-D.	Adenine Nucleotides	55-73	peptidylprolyl isomerase D	Homo sapiens	175-188	
23598413-4	2013	Then SIRT3 deacetylated cyclophilin D, diminished its peptidyl-prolyl cis-trans isomerase activity and induced its dissociation from the adenine nucleotide translocator.	Adenine Nucleotides	137-155	peptidylprolyl isomerase D	Homo sapiens	24-37	
20490903-7	2010	Phosphorylated GSK-3beta inhibits mPTP opening presumably by multiple mechanisms, including preservation of hexokinase II in mPTP complex, prevention of interaction of cyclophilin-D with adenine nucleotide translocase, inhibition of p53 activation and attenuation of ATP hydrolysis during ischemia.	Adenine Nucleotides	187-205	peptidylprolyl isomerase D	Homo sapiens	168-181	
20159966-2	2010	Sirtuin-3 deacetylates cyclophilin D, diminishing its peptidyl-prolyl cis-trans isomerase activity and inducing its dissociation from the adenine nucleotide translocator.	Adenine Nucleotides	138-156	peptidylprolyl isomerase D	Homo sapiens	23-36	
28428752-6	2017	In addition to inhibit CypD binding to adenine nucleotide translocator, GA potentiates extracellular signal-regulated kinases (ERK) phosphorylation, leading to a decrease in cyclophilin D (CypD) expression, resulting in a desensitization to induction of MPTP, thus inhibiting caspase activation and ultimately giving rise to cellular survival.	Adenine Nucleotides	39-57	peptidylprolyl isomerase D	Homo sapiens	23-27