PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24973540-4 2014 A chemiluminescent biosensor, developed using the different properties of G-rich DNA aptamer-conjugated 6-FAM in the absence and presence of PSA in guanine chemiluminescence reaction, was able to quantify trace levels of PSA in human serum within 30 min without time-consuming and complicated procedures (e.g., multiple incubation and washings) required for conventional immunoassays operated with expensive and intractable antibodies. 6-carboxyfluorescein 104-109 kallikrein related peptidase 3 Homo sapiens 141-144 30367880-5 2019 With the increase of PSA concentration, the strength of the red light emitted from Texas Red dropped exponentially, whereas with the increase of VEGF concentration, the green light emitted from 6-FAM was enhanced. 6-carboxyfluorescein 194-199 kallikrein related peptidase 3 Homo sapiens 21-24 24973540-1 2014 Using guanine (G)-rich DNA aptamer-conjugated 6-carboxyfluorescein (6-FAM) capable of rapidly capturing prostate specific antigen (PSA) in human serum, cost-effective and simple biosensor with guanine chemiluminescence detection was developed for early diagnosis of prostate cancer. 6-carboxyfluorescein 46-66 kallikrein related peptidase 3 Homo sapiens 104-135 24973540-1 2014 Using guanine (G)-rich DNA aptamer-conjugated 6-carboxyfluorescein (6-FAM) capable of rapidly capturing prostate specific antigen (PSA) in human serum, cost-effective and simple biosensor with guanine chemiluminescence detection was developed for early diagnosis of prostate cancer. 6-carboxyfluorescein 68-73 kallikrein related peptidase 3 Homo sapiens 104-135 24973540-3 2014 However, G-rich DNA aptamer-conjugated 6-FAM bound with PSA cannot emit light because PSA acts as a strong interference in CRET between 6-FAM and high-energy intermediate formed from the reaction of 3,4,5-trimethoxylphenylglyoxal (TMPG) and guanine of G-rich DNA aptamer. 6-carboxyfluorescein 39-44 kallikrein related peptidase 3 Homo sapiens 56-59 24973540-3 2014 However, G-rich DNA aptamer-conjugated 6-FAM bound with PSA cannot emit light because PSA acts as a strong interference in CRET between 6-FAM and high-energy intermediate formed from the reaction of 3,4,5-trimethoxylphenylglyoxal (TMPG) and guanine of G-rich DNA aptamer. 6-carboxyfluorescein 39-44 kallikrein related peptidase 3 Homo sapiens 86-89 24973540-3 2014 However, G-rich DNA aptamer-conjugated 6-FAM bound with PSA cannot emit light because PSA acts as a strong interference in CRET between 6-FAM and high-energy intermediate formed from the reaction of 3,4,5-trimethoxylphenylglyoxal (TMPG) and guanine of G-rich DNA aptamer. 6-carboxyfluorescein 136-141 kallikrein related peptidase 3 Homo sapiens 56-59 24973540-3 2014 However, G-rich DNA aptamer-conjugated 6-FAM bound with PSA cannot emit light because PSA acts as a strong interference in CRET between 6-FAM and high-energy intermediate formed from the reaction of 3,4,5-trimethoxylphenylglyoxal (TMPG) and guanine of G-rich DNA aptamer. 6-carboxyfluorescein 136-141 kallikrein related peptidase 3 Homo sapiens 86-89 24973540-4 2014 A chemiluminescent biosensor, developed using the different properties of G-rich DNA aptamer-conjugated 6-FAM in the absence and presence of PSA in guanine chemiluminescence reaction, was able to quantify trace levels of PSA in human serum within 30 min without time-consuming and complicated procedures (e.g., multiple incubation and washings) required for conventional immunoassays operated with expensive and intractable antibodies. 6-carboxyfluorescein 104-109 kallikrein related peptidase 3 Homo sapiens 221-224