PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15161039-6 2004 The activity of MRP1 p-glycoprotein was studied in human breast cancer cell lines such as HTB-26/MRP1 and two MRP-negative breast cancer cell lines, T47D and MCF7, by carboxyfluorescein accumulation, and on a stomach cancer cell line. 6-carboxyfluorescein 167-185 ATP binding cassette subfamily C member 1 Homo sapiens 16-20 15161039-6 2004 The activity of MRP1 p-glycoprotein was studied in human breast cancer cell lines such as HTB-26/MRP1 and two MRP-negative breast cancer cell lines, T47D and MCF7, by carboxyfluorescein accumulation, and on a stomach cancer cell line. 6-carboxyfluorescein 167-185 ATP binding cassette subfamily C member 1 Homo sapiens 16-19 15161039-11 2004 The MRP-mediated carboxyfluorescein accumulation in HTB-26/MRP human breast cancer cells and daunorubicin accumulation in human stomach cancer cells 257P/MDR were not modified by these alis compounds. 6-carboxyfluorescein 17-35 ATP binding cassette subfamily C member 1 Homo sapiens 4-7 9676848-1 1998 To develop a functional assay for the activity of the multidrug resistance protein 1 (MRP1), we tested whether carboxyfluorescein (CF) was specifically transported by MRP and whether this transport pump could be specifically blocked by the leukotriene D4 receptor antagonist MK-571. 6-carboxyfluorescein 111-129 ATP binding cassette subfamily C member 1 Homo sapiens 86-89 11587212-4 2001 P-gp and MRP activity varied strongly between the cases (rhodamine 123 efflux-blocking by PSC833: 5.4+/-7.7, and carboxyfluorescein efflux-blocking by MK-571: 4.3+/-6.7, n = 60). 6-carboxyfluorescein 113-131 ATP binding cassette subfamily C member 1 Homo sapiens 9-12 10955805-3 2000 In the present study, the functional activity of P-gp and MRP was determined in 104 de novo AML patients with a flow cytometric assay using rhodamine 123 (Rh123) in combination with PSC833 and carboxyfluorescein (CF) in combination with MK-571. 6-carboxyfluorescein 193-211 ATP binding cassette subfamily C member 1 Homo sapiens 58-61 10828037-4 2000 Functional activity of multidrug resistance protein (MRP) was studied in a flow cytometric assay with the use of the MRP substrate carboxyfluorescein (CF) and the inhibitor MK-571. 6-carboxyfluorescein 131-149 ATP binding cassette subfamily C member 1 Homo sapiens 23-51 10828037-4 2000 Functional activity of multidrug resistance protein (MRP) was studied in a flow cytometric assay with the use of the MRP substrate carboxyfluorescein (CF) and the inhibitor MK-571. 6-carboxyfluorescein 131-149 ATP binding cassette subfamily C member 1 Homo sapiens 53-56 10828037-4 2000 Functional activity of multidrug resistance protein (MRP) was studied in a flow cytometric assay with the use of the MRP substrate carboxyfluorescein (CF) and the inhibitor MK-571. 6-carboxyfluorescein 131-149 ATP binding cassette subfamily C member 1 Homo sapiens 117-120 15076236-7 2004 P-gp and MRP1 functions were assayed using rhodamine 123 (Rh123) and carboxyfluorescein (CF) efflux assays, respectively. 6-carboxyfluorescein 69-87 ATP binding cassette subfamily C member 1 Homo sapiens 9-13 12879156-1 2003 We employed human red blood cells as a model system to check the affinity of MRP1 (Multidrug Resistance-associated Protein 1) towards fluorescein and a set of its carboxyl derivatives: 5/6-carboxyfluorescein (CF), 2",7"-bis-(2-carboxyethyl)-5/6-carboxyfluorescein (BCECF) and calcein (CAL). 6-carboxyfluorescein 187-207 ATP binding cassette subfamily C member 1 Homo sapiens 77-81 12879156-1 2003 We employed human red blood cells as a model system to check the affinity of MRP1 (Multidrug Resistance-associated Protein 1) towards fluorescein and a set of its carboxyl derivatives: 5/6-carboxyfluorescein (CF), 2",7"-bis-(2-carboxyethyl)-5/6-carboxyfluorescein (BCECF) and calcein (CAL). 6-carboxyfluorescein 187-207 ATP binding cassette subfamily C member 1 Homo sapiens 83-124 11986786-6 2002 Interaction of rhein with multidrug resistance-associated protein 1 was studied by carboxy fluorescein efflux and direct cytotoxicity by apoptosis induction. 6-carboxyfluorescein 83-102 ATP binding cassette subfamily C member 1 Homo sapiens 26-67 18990976-5 2008 Carboxyfluorescein (CF) was used as a model MRP1 substrate and was measured with functional flow cytometry. 6-carboxyfluorescein 0-18 ATP binding cassette subfamily C member 1 Homo sapiens 44-48 33015009-7 2020 MRP1 activity was assessed by bidirectional transport and efflux experiments using the MRP1 substrate, 5(6)-carboxyfluorescein [CF; formed intracellularly from 5(6)-carboxyfluorescein-diacetate (CFDA)] in AT1-like and NCI-H441 cell monolayers. 6-carboxyfluorescein 103-126 ATP binding cassette subfamily C member 1 Homo sapiens 0-4 33015009-7 2020 MRP1 activity was assessed by bidirectional transport and efflux experiments using the MRP1 substrate, 5(6)-carboxyfluorescein [CF; formed intracellularly from 5(6)-carboxyfluorescein-diacetate (CFDA)] in AT1-like and NCI-H441 cell monolayers. 6-carboxyfluorescein 103-126 ATP binding cassette subfamily C member 1 Homo sapiens 87-91 33015009-7 2020 MRP1 activity was assessed by bidirectional transport and efflux experiments using the MRP1 substrate, 5(6)-carboxyfluorescein [CF; formed intracellularly from 5(6)-carboxyfluorescein-diacetate (CFDA)] in AT1-like and NCI-H441 cell monolayers. 6-carboxyfluorescein 128-130 ATP binding cassette subfamily C member 1 Homo sapiens 0-4 33015009-7 2020 MRP1 activity was assessed by bidirectional transport and efflux experiments using the MRP1 substrate, 5(6)-carboxyfluorescein [CF; formed intracellularly from 5(6)-carboxyfluorescein-diacetate (CFDA)] in AT1-like and NCI-H441 cell monolayers. 6-carboxyfluorescein 128-130 ATP binding cassette subfamily C member 1 Homo sapiens 87-91 24672635-4 2014 The transport of carboxyfluorescein, a known MRP1 substrate, was measured by functional flow cytometry to evaluate MRP1 activity. 6-carboxyfluorescein 17-35 ATP binding cassette subfamily C member 1 Homo sapiens 45-49 24672635-4 2014 The transport of carboxyfluorescein, a known MRP1 substrate, was measured by functional flow cytometry to evaluate MRP1 activity. 6-carboxyfluorescein 17-35 ATP binding cassette subfamily C member 1 Homo sapiens 115-119 18990976-5 2008 Carboxyfluorescein (CF) was used as a model MRP1 substrate and was measured with functional flow cytometry. 6-carboxyfluorescein 20-22 ATP binding cassette subfamily C member 1 Homo sapiens 44-48 17912704-5 2007 In the human bronchial epithelial cell line 16HBE14o-, MRP1 function was studied flow cytometrically by cellular retention of carboxyfluorescein (CF) after CSE incubation and MRP1 downregulation by RNA interference (siRNA). 6-carboxyfluorescein 126-144 ATP binding cassette subfamily C member 1 Homo sapiens 55-59