PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1137717-11	1975	In beta-sitosterol-fed animals, the reductase was increased 2-fold and cholesterol 7 alpha-hydroxylase was not significantly different from controls.	gamma-sitosterol	3-18	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	71-102	
2747437-12	1989	The possibility is discussed that the hypercholesterolemia obtained in the beta-sitosterol-infused rats is due to the inhibitory effect of sitosterol on the cholesterol 7 alpha-hydroxylase.	gamma-sitosterol	75-90	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	157-188	
2747437-12	1989	The possibility is discussed that the hypercholesterolemia obtained in the beta-sitosterol-infused rats is due to the inhibitory effect of sitosterol on the cholesterol 7 alpha-hydroxylase.	gamma-sitosterol	80-90	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	157-188	
4729973-6	1973	Rats fed sitosterol plus taurocholate had nearly normal HMG CoA reductase activity, but cholesterol 7alpha-hydroxylase was inhibited and biliary cholesterol remained high.	gamma-sitosterol	9-19	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	88-118	
8020891-0	1994	The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.	gamma-sitosterol	32-42	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	116-147	
8020891-6	1994	However, hepatic cholesterol 7 alpha-hydroxylase activity was inhibited 30% in both the sitosterolemic homozygotes and rats with high liver sitosterol concentrations.	gamma-sitosterol	88-98	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	17-48	
3143743-5	1988	Cholestanol and sitosterol competitively inhibited cholesterol 7 alpha-hydroxylase in both rat and human liver microsomes, with cholestanol the more potent inhibitor.	gamma-sitosterol	16-26	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	51-82	
4729973-4	1973	Dietary sitosterol produced increases in the specific activity of HMG CoA reductase (3.6-fold) and cholesterol 7alpha-hydroxylase (1.4-fold), and biliary cholesterol concentrations in this group more than doubled.	gamma-sitosterol	8-18	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	99-129