PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18370551-2	1998	OBJECTIVE: This trial reports the 6-month results of a pilot study using lymphoblastoid interferon alpha (IFNalpha) and acetylcysteine (N-acetylcysteine) separately and in combination in patients with chronic hepatitis C, genotype 1b, who were nonresponders to previous treatment with recombinant IFNalpha alone.	Acetylcysteine	120-134	interferon alpha 1	Homo sapiens	297-305	
11278370-6	2001	The ability of IFN-alpha and vanadate to induce apoptosis did not require expression of p53 and was blocked by N-acetyl-l-cysteine.	Acetylcysteine	111-130	interferon alpha 1	Homo sapiens	15-24	
18370551-2	1998	OBJECTIVE: This trial reports the 6-month results of a pilot study using lymphoblastoid interferon alpha (IFNalpha) and acetylcysteine (N-acetylcysteine) separately and in combination in patients with chronic hepatitis C, genotype 1b, who were nonresponders to previous treatment with recombinant IFNalpha alone.	Acetylcysteine	136-152	interferon alpha 1	Homo sapiens	297-305	
8228388-6	1993	In IFN-unresponsive patients, the addition of 600 mg tid of oral N-acetyl cysteine (NAC), a glutathione precursor, resulted in a steady decrease of ALT values in all patients, with complete normalization in 41% of cases after 5-6 months of combined therapy.	Acetylcysteine	65-82	interferon alpha 1	Homo sapiens	3-6	
8228388-6	1993	In IFN-unresponsive patients, the addition of 600 mg tid of oral N-acetyl cysteine (NAC), a glutathione precursor, resulted in a steady decrease of ALT values in all patients, with complete normalization in 41% of cases after 5-6 months of combined therapy.	Acetylcysteine	84-87	interferon alpha 1	Homo sapiens	3-6	
8228388-8	1993	Supplementation of IFN with NAC induced a near normalization of intralymphocytic glutathione, but plasma levels were only moderately increased.	Acetylcysteine	28-31	interferon alpha 1	Homo sapiens	19-22	
8228388-10	1993	In conclusion, NAC enhances the response to IFN in CHC.	Acetylcysteine	15-18	interferon alpha 1	Homo sapiens	44-47	
31196186-15	2019	Treatment of leukemic cell lines with NAC prevented the DFX-mediated phosphorylation of STAT1 as well as the expression of the IFN-stimulated genes.	Acetylcysteine	38-41	interferon alpha 1	Homo sapiens	127-130	
28623559-5	2017	Importantly, the ROS scavenger N-acetyl cysteine (NAC) prevented mitochondrial dysfunctions, type I IFN-stimulated transcript levels, inflammatory cell infiltrate, and muscle weakness in an experimental autoimmune myositis mouse model.	Acetylcysteine	31-48	interferon alpha 1	Homo sapiens	100-103	
28623559-5	2017	Importantly, the ROS scavenger N-acetyl cysteine (NAC) prevented mitochondrial dysfunctions, type I IFN-stimulated transcript levels, inflammatory cell infiltrate, and muscle weakness in an experimental autoimmune myositis mouse model.	Acetylcysteine	50-53	interferon alpha 1	Homo sapiens	100-103	
22825687-11	2012	In the femoral head, co-treatment with NAC and MPSL significantly decreased the expression of TRIM21 at 3 h and significantly increased the expression of interferon (IFN)-alpha at 24 h when compared with the MPSL group.	Acetylcysteine	39-42	interferon alpha 1	Homo sapiens	154-176	
23590859-0	2013	N-acetyl-cysteine prevents toxic oxidative effects induced by IFN-alpha in human neurons.	Acetylcysteine	0-17	interferon alpha 1	Homo sapiens	62-71	
23590859-9	2013	A co-treatment with N-acetyl-cysteine (NAC; 5 mm), a potent antioxidant and mitochondrial modulator, was able to counteract all of these IFN-alpha-induced effects.	Acetylcysteine	20-37	interferon alpha 1	Homo sapiens	137-146	
23590859-9	2013	A co-treatment with N-acetyl-cysteine (NAC; 5 mm), a potent antioxidant and mitochondrial modulator, was able to counteract all of these IFN-alpha-induced effects.	Acetylcysteine	39-42	interferon alpha 1	Homo sapiens	137-146	
23590859-11	2013	We suggest that NAC, already tested for the treatment of psychiatric disorders, may be useful to prevent IFN-alpha-induced central side-effects in a safe and effective way.	Acetylcysteine	16-19	interferon alpha 1	Homo sapiens	105-114