PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21131394-10	2011	The changes in oxidant/antioxidant enzymes and IL-6 release were reversed by the antioxidants N-acetyl-cysteine (NAC) and ebselen through inhibition of Smad3 phosphorylation, indicating redox-dependent activation of Smad3 by TGF-beta.	Acetylcysteine	94-111	SMAD family member 3	Homo sapiens	152-157	
21131394-10	2011	The changes in oxidant/antioxidant enzymes and IL-6 release were reversed by the antioxidants N-acetyl-cysteine (NAC) and ebselen through inhibition of Smad3 phosphorylation, indicating redox-dependent activation of Smad3 by TGF-beta.	Acetylcysteine	94-111	SMAD family member 3	Homo sapiens	216-221	
21131394-10	2011	The changes in oxidant/antioxidant enzymes and IL-6 release were reversed by the antioxidants N-acetyl-cysteine (NAC) and ebselen through inhibition of Smad3 phosphorylation, indicating redox-dependent activation of Smad3 by TGF-beta.	Acetylcysteine	113-116	SMAD family member 3	Homo sapiens	152-157	
21131394-10	2011	The changes in oxidant/antioxidant enzymes and IL-6 release were reversed by the antioxidants N-acetyl-cysteine (NAC) and ebselen through inhibition of Smad3 phosphorylation, indicating redox-dependent activation of Smad3 by TGF-beta.	Acetylcysteine	113-116	SMAD family member 3	Homo sapiens	216-221	
16098950-3	2005	Dissection of the molecular steps involved in TGF-beta signaling revealed that N-acetyl-L-cysteine dose-dependently abrogated the induction of the TGF-beta1 signaling reporter gene activation, the phosphorylation of Smad2 and Smad3, and the up-regulation of Smad7 mRNA.	Acetylcysteine	79-98	SMAD family member 3	Homo sapiens	226-231	
34687772-6	2021	Removal of ROS by N-acetylcysteine significantly reduced ER stress in prostate cancer cells, followed by the decrease of Smad3 phosphorylation and expression of nuclear Snail, resulting in the inhibition of EMT and malignant phenotypic changes of prostate cancer cells.	Acetylcysteine	18-34	SMAD family member 3	Homo sapiens	121-126