PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10630730-2	2000	Because some beta-adrenergic receptor antagonists such as cyanopindolol are used as 5-HT1A/5-HT1B receptor antagonists, we tested the hypothesis that bucindolol can interact with 5-HT receptors.	bucindolol	150-160	5-hydroxytryptamine receptor 1A	Rattus norvegicus	84-90	
10630730-4	2000	In binding studies, bucindolol displayed high affinity for the 5-HT1A receptor (Ki, 11 nM), modest affinity for the 5-HT2A receptor (Ki, 382 nM), and no measurable affinity for the 5-HT1D receptor; binding affinity for the 5-HT2B receptor was not studied.	bucindolol	20-30	5-hydroxytryptamine receptor 1A	Rattus norvegicus	63-69	
10630730-12	2000	Thus, these data suggest that bucindolol lacks the ability to activate the 5-HT1A, 5-HT1D, 5-HT2A, and 5-HT2B receptor, but can block alpha1-adrenergic receptors and act as a weak 5-HT2A- and 5-HT2B-receptor antagonist.	bucindolol	30-40	5-hydroxytryptamine receptor 1A	Rattus norvegicus	75-81