PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6208535-8 1984 Modification of arginine residues in ACE with cyclohexanedione or butanedione similarly inhibited hydrolysis of SP, bradykinin and Bz-Gly-Phe-Arg (80-93%) indicating an active site arginine is required for hydrolysis of SP. Diacetyl 66-77 angiotensin I converting enzyme Homo sapiens 37-40 2992465-4 1985 Finally a butanedione treatment increased thermolysin activity, but abolished ACE activity; it reduced "enkephalinase" activity by 80% when measured with a free C-terminal carboxylate enkephalin analogue but only slightly with the corresponding amidated derivative. Diacetyl 10-21 angiotensin I converting enzyme Homo sapiens 78-81