PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22821656-6 2012 RESULTS: Caf inhibited the production of NO, TNF-alpha and IL-1beta induced by LPS treatment in primary microglia in a dose-dependent manner. cafestol palmitate 9-12 tumor necrosis factor Rattus norvegicus 45-54 22821656-9 2012 Caf could also significantly inhibit the up-regulation of iNOS, TNF-alpha, and IL-1beta gene expressions in ischemic cerebral tissues. cafestol palmitate 0-3 tumor necrosis factor Rattus norvegicus 64-73 16198523-12 2006 In the in vitro experiments, CAF significantly reduced TNF-alpha and TGF-beta1 levels in culture supernatants of KCs. cafestol palmitate 29-32 tumor necrosis factor Rattus norvegicus 55-64 16198523-13 2006 The results showed CAF significantly inhibited the progression of hepatic fibrosis induced by CCl(4), and the inhibitory effect of CAF on hepatic fibrosis might be associated with its ability to scavenge free radical and inhibit the production of TNF-alpha and TGF-beta1 from activated KCs. cafestol palmitate 131-134 tumor necrosis factor Rattus norvegicus 247-256 34605386-10 2021 However, there was a decrease in IL-6 in the liver (DHA/EPA effect: p = 0.023) and TNF-alpha in the brain (CAF compared to CAF+DHA/EPA, p < 0.05). cafestol palmitate 107-110 tumor necrosis factor Rattus norvegicus 83-92 34535697-7 2021 At PND25, CAF offspring had: (1) higher percentage of fat content, and were lighter; (2) sex-specific differences in levels of glucose; (3) higher levels of interleukin 6 (IL-6), interleukin-10 (IL-10) and tumor necrosis factor (TNF-alpha); (4) sex-specific differences in concentration of IL-6 and TNF-alpha, with an increase in CAF females; (5) higher level of IL-10 in both sexes, with a more pronounced increase in females. cafestol palmitate 10-13 tumor necrosis factor Rattus norvegicus 299-308 31035432-3 2019 CAF diet enhanced the intestinal permeation of an orally administered marker (ovalbumin, OVA) and increased the plasma levels of tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharides (LPS) in 2-3-fold. cafestol palmitate 0-3 tumor necrosis factor Rattus norvegicus 129-156 31035432-3 2019 CAF diet enhanced the intestinal permeation of an orally administered marker (ovalbumin, OVA) and increased the plasma levels of tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharides (LPS) in 2-3-fold. cafestol palmitate 0-3 tumor necrosis factor Rattus norvegicus 158-167 30245181-6 2018 The CAF diet increased OVA, LPS, MPO and TNF-alpha levels, accompanied by decreased TEER values in the small and large intestines. cafestol palmitate 4-7 tumor necrosis factor Rattus norvegicus 41-50 28132653-7 2017 TNF-alpha was overexpressed in the ileum of both CAF diet and fa/fa groups, and ileal inflammation was associated with the degree of obesity and metabolic alterations. cafestol palmitate 49-52 tumor necrosis factor Rattus norvegicus 0-9 33155397-7 2021 RESULTS: CAF diet increased weight gain, visceral fat, and plasma glucose, triglyceride, and TNF-alpha levels. cafestol palmitate 9-12 tumor necrosis factor Rattus norvegicus 93-102