PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9461577-2	1998	TK1 is cell cycle-regulated; TK2 is expressed constitutively and can phosphorylate deoxycytidine to the same extent as thymidine.	Deoxycytidine	83-96	thymidine kinase 1	Homo sapiens	0-3	
18455811-5	2008	FHV TK and CHV TK differ in substrate recognition from mammalian cytosolic thymidine kinase 1 (TK1) in that TK1 does not phosphorylate BVDU and they also differ from mammalian mitochondrial thymidine kinase 2 (TK2), which, in addition to thymidine and thymidine analogs also phosphorylates dCyd.	Deoxycytidine	290-294	thymidine kinase 1	Homo sapiens	95-98	
18455811-5	2008	FHV TK and CHV TK differ in substrate recognition from mammalian cytosolic thymidine kinase 1 (TK1) in that TK1 does not phosphorylate BVDU and they also differ from mammalian mitochondrial thymidine kinase 2 (TK2), which, in addition to thymidine and thymidine analogs also phosphorylates dCyd.	Deoxycytidine	290-294	thymidine kinase 1	Homo sapiens	108-111	
2241101-6	1990	In order to confirm the existence of TK1, particular at pl value 5.3, the ability of the isoenzymes to use different phosphor donors (ATP and uridinetriphosphate (UTP)) and substrates (TdR and deoxycytidine (dCdR) was also studied.	Deoxycytidine	193-206	thymidine kinase 1	Homo sapiens	37-40	
32189555-12	2020	These results demonstrate the pharmacokinetic importance of characterizing the expression and activity of TK1 and dCK during chemotherapy with thymidine and deoxycytidine analogs in order to optimize their efficacy.	Deoxycytidine	157-170	thymidine kinase 1	Homo sapiens	106-109	
22385435-5	2012	In CeTK1, some of these mutations led to increased activity with deoxycytidine and deoxyguanosine, two unusual substrates for TK1-like kinases.	Deoxycytidine	65-78	thymidine kinase 1	Homo sapiens	5-8